- Enrolling by invitation
CARDiac Toxicity Following ImmunOtherapy Treatment for Melanoma
This study looks at how immunotherapy for melanoma might affect the heart in the long term. Researchers want to see if it's possible to check for heart-related side effects years after treatment, hoping to improve future care for patients.
For: Melanoma Stage III or IVUnited Kingdom - Active not recruiting
CARDIO-TTRansform Magnetic Resonance Imaging (MRI) Sub-study
This study uses special heart scans (MRI) to see if a new medicine can help reduce a build-up of a substance called amyloid in the hearts of people with a condition called ATTR-CM. The scans will help doctors understand how the medicine affects the heart over time.
For: Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR-CM)United States · Italy · Spain - Recruiting
Cardiomyopathies and Heart Muscle Diseases: Cardiac Imaging in the Evaluation of Myocardial Fibrosis Transition
This study is looking at heart scarring, called fibrosis, in different heart muscle conditions. We're using a special scan with a new dye to better understand this scarring and how it changes over time. The aim is to find new ways to diagnose and treat these heart problems.
For: Heart Failure With Preserved Ejection Fraction · Hypertrophic Cardiomyopathy · Cardiac SarcoidosisUnited Kingdom - Active not recruitingNA
Endothelin Role In COronary Microcirculation
This study looks into why some people have chest pain even with clear heart arteries. It explores if a medicine called bosentan can improve how tiny blood vessels in the heart work by targeting a natural body chemical.
For: Coronary Microvascular Dysfunction (CMD) · Angina Pectoris With Normal Coronary Arteriogram · Microvascular AnginaUnited Kingdom - Active not recruiting
Residual Inflammation and Plaque Progression Long-term Evaluation
This study looks at how inflammation in blood vessels after a heart attack might lead to future problems. We use special scans to see inflammation and track changes in blood vessels over time. The goal is to understand how to better prevent future heart issues.
For: Atherosclerosis · Myocardial Infarction · Coronary Artery DiseaseUnited Kingdom - Recruiting
Effects of Pulmonary Diseases and Their Treatment on Cardiac Function
This study looks at how long-term lung diseases like COPD, asthma, or lung scarring affect the heart, especially the left side. Researchers will use special scans to see if treatments for lung problems also help the heart, aiming for better care.
For: COPD · Bronchial Asthma · Idiopathic Pulmonary FibrosisGermany - Recruiting
Prospective Evaluation of the Biomechanical Properties of the Thoracic Aorta Coupling Magnetic Resonance Imaging and In-vitro Elasticity Tests in Patients With Ascending Aortic Aneurysm
This study looks at how strong and stretchy a part of the main heart artery (aorta) is in people needing surgery for a bulge (aneurysm). It uses special scans and tests to help doctors understand the aorta better and improve how they decide on and monitor treatments.
For: Patient With Ascending Aortic Aneurysm With Surgical Indication for ReplacementFrance