- Active not recruitingPHASE1
A Study Evaluating Safety and Tolerability, and Pharmacokinetics of Navitoclax Monotherapy and in Combination With Ruxolitinib in Participants With Myeloproliferative Neoplasm
This study looks at a new drug, navitoclax, alone or with an existing drug, ruxolitinib, for a group of blood cancers called myeloproliferative neoplasms. Researchers want to see if it's safe, how the body handles it, and if it affects other drugs.
For: Myeloproliferative NeoplasmUnited States · Belgium · Bulgaria - Active not recruitingPHASE2, PHASE3
Systemic Therapy in Advancing or Metastatic Prostate Cancer: Evaluation of Drug Efficacy
This study, called STAMPEDE, looks for better ways to treat prostate cancer that is spreading or has a high chance of spreading. It tests new treatments against standard ones to help men live longer and have a better quality of life.
For: Prostate CancerSwitzerland · United Kingdom - Active not recruitingPHASE4
Effect of Celecoxib on Postoperative Analgesia and Disease Severity in AERD Patients with CRS
This study is looking at whether a medicine called celecoxib can help people with sinus problems and aspirin allergy feel better after surgery. We want to see if it reduces pain and swelling, making recovery easier without causing new issues.
For: Chronic Rhinosinusitis with Nasal Polyps · Aspirin-exacerbated Respiratory DiseaseCanada · Saudi Arabia