- Not yet recruitingNA
Financial Incentives and Weight Loss in Failed Bariatric Surgery
This study looks at whether financial rewards can help people who have regained weight after weight-loss surgery. It explores if a reward system encourages people to achieve and maintain their weight loss goals, and if it's a good way for the health service to help in the future.
For: Obesity · Obesity RecidivismFrance - Active not recruitingNA
WB-EMS Effects on Cardiometabolic Risk Factors
This study looks at how a type of exercise called whole-body electrical stimulation (WB-EMS) affects blood pressure and other health factors in men over 50. It wants to see if this quick, joint-friendly exercise can help people with slightly high blood pressure.
For: Hypertension · Metabolic Syndrome · HypercholesterolemiaGermany - RecruitingPHASE3
Safety and Efficacy of APC-0101 in Preterm Infants With Respiratory Distress Syndrome
This study is looking at a new medicine called APC-0101 for premature babies with breathing problems (Respiratory Distress Syndrome). It compares giving this medicine with standard breathing support to just giving standard support, to see if it's safe and helps babies breathe better and grow well.
For: Respiratory Distress Syndrome · Pre-term InfantsUnited States · Canada · United Kingdom - Not yet recruitingPHASE3
Trial to Assess the Efficacy and Safety During Convective Radiofrequency Water Vapor Thermal Therapy (REZUM) for Benign Prostate Hyperplasia
This study looks at different ways to manage pain during a procedure called Rezum for an enlarged prostate. It compares a combination of pain medicines taken by mouth with a deeper sleep medicine given through a vein, aiming to find which is better for comfort.
For: Benign Prostate Hypertrophy(BPH)Canada - RecruitingNA
Does the Development of the Repeated Bout Effect Depend on Oxidative Stress and Inflammation?
This study looks at how vitamin C and ibuprofen affect muscle soreness after exercise. We want to see if these common supplements stop your body from getting used to exercise and becoming less sore over time. This is important for athletes.
For: Exercise RecoveryUnited Kingdom - Active not recruitingNA
Quantra® System With the QPlus® Cartridge in Double-lung Transplantation
This study looks at whether a special blood test, called Quantra, can help reduce the amount of blood transfusions needed during double-lung transplant surgery, aiming to improve patient outcomes.
For: Lung Diseases · Transplant-Related DisorderFrance - RecruitingNA
Influence of Preoperative Immunomodulation by Oral Impact on Postoperative Complications Following Cystectomies & Nephrectomies
This study looks at whether a special nutritional drink called Oral Impact can help patients recovering from major bladder or kidney surgery. Researchers want to see if taking this drink before surgery reduces problems afterwards and helps patients go home sooner.
For: Urological ManifestationsFrance - Active not recruitingNA
Evaluating the Effects of Prebiotics on Sleep, the Gut Microbiome, Cognition, Immune Function and Stress
This study looks at how special fibres called prebiotics might affect sleep, gut health, thinking, immune system, and stress in healthy adults who often struggle with poor sleep. It compares different prebiotic mixtures to a dummy pill over 56 days.
For: SleepUnited Kingdom - RecruitingPHASE3
Implementation of Metformin theraPy to Ease Decline of Kidney Function in Polycystic Kidney Disease (IMPEDE-PKD)
This study looks at whether metformin, a common diabetes drug, can help slow down kidney disease in people with Polycystic Kidney Disease (ADPKD). The goal is to improve health and quality of life for those affected.
For: Autosomal Dominant Polycystic Kidney DiseaseAustralia · New Zealand · United Kingdom - RecruitingNA
Frailty Rehabilitation
This study looks at how a special program can help older adults who are a bit frail. It checks if combining exercise, better food, and checking medicines can improve their health and daily life, compared to just exercise or usual care.
For: FrailtyCanada - Active not recruitingNA
A Culturally-tailored Personalized Nutrition Intervention in South Asian Women at Risk of Gestational Diabetes
This study looks at how a special healthy eating plan, created for South Asian women, can help manage blood sugar during pregnancy. It aims to prevent gestational diabetes and improve health for both mother and baby.
For: Diabetes, GestationalCanada - Active not recruitingNA
The TEACH (Texting After ACS Discharge) Pilot Randomized Trial
This study looks at whether sending text messages can help people who have recently had a heart attack. It aims to see if texting can support their recovery, encourage them to take their medicines, and reduce how often they need to go back to hospital.
For: Coronary Artery DiseaseCanada - RecruitingNA
Bioavailability of Human Milk Oligosaccharides in Healthy Adults
This study looks at how the special sugars found in human milk, called HMOs, are used by healthy adults. We want to see if these sugars get into the bloodstream, as they might have benefits beyond digestion, like helping our immune system.
For: HealthyGermany - Not yet recruitingNA
Early Recovery After Surgery (ERAS)/Prehabilitation - Randomized Controlled Trial on the Implementation of ERAS/prehabilitation in Elective Reconstructive Shoulder Surgery
This study looks at whether preparing for shoulder surgery with exercises and information (called 'prehabilitation') helps people recover better and feel more satisfied afterwards. It compares this preparation to standard care for adults having surgery for a torn rotator cuff.
For: Rotator CuffGermany - RecruitingNA
Safety and Effectiveness of Mechanical Thrombectomy Using the Anaconda ANA Funnel Catheter
This study looks at a new device called the ANA Funnel Catheter to treat a severe type of stroke. It aims to see if this new tool is safe and helps doctors remove blood clots more effectively from the brain, potentially improving recovery for patients.
For: Acute Ischemic Stroke From Large Vessel OcclusionUnited States · France · Hungary - RecruitingNA
The Effect of Ketone Monoesters on Skeletal Muscle Protein Synthesis and Whole-body Protein Metabolism.
This study looks at how a special drink called a ketone monoester, taken with protein, affects muscle growth and repair in healthy young adults. We want to see if it can help muscles get stronger and recover better.
For: Healthy ParticipantsUnited Kingdom - RecruitingNA
Investigating the Feasibility of Krill Oil Intervention to Improve Muscle Function in Adults With Long-term Conditions
This study looks at whether krill oil can improve muscle strength in adults with long-term health conditions. Participants will take krill oil or a dummy pill for 12 weeks, with researchers measuring muscle function and other health markers.
For: Krill Oil · Muscle Function · Grip StrengthUnited Kingdom - Active not recruitingPHASE2
Healthy Ageing: a Feasibility Study to Evaluate Digitally-enabled Ways to Support Healthy Ageing
This study looks at how digital tools, like smartwatches, can help older adults stay healthy. Researchers want to see if these tools are easy to use and if they can encourage people over 65 to adopt healthier habits, like being more active.
For: Frailty · Older Adults (65 Years and Older) · Digital Health InterventionUnited Kingdom - RecruitingNA
Fast Food Online Delivery Purchase Behaviour in the Presence and Absence of Price-based Incentives
This study looks at how removing special offers on takeaways affects what people order. Researchers want to see if removing discounts helps people choose healthier fast food options, comparing real-life choices with previous studies based on hypothetical decisions.
For: Food Purchases · Eating BehaviourUnited Kingdom - Active not recruitingNA
Taxifolin/Ergothioneine and Immune Biomarkers in Healthy Volunteers (TaxEr)
This study looks at how natural substances, Taxifolin and Ergothioneine, found in foods like apples and mushrooms, might affect our immune system. We want to see if these substances can help improve how our body fights off illness, especially as we get older, by reducing stress on our cells.
For: Antioxidative Stress · Cold · InfluenzaUnited Kingdom - Not yet recruitingNA
Neurophysiological Mechanisms of Placebo and Nocebo Effects in Sports - a Protocol Paper
This study explores how our beliefs (positive or negative expectations) can impact sports performance. Researchers will use brainwave tests (EEG) and leg strength measurements to understand how these 'placebo' and 'nocebo' effects work in the brain.
For: Placebo Effect · Nocebo EffectUnited Kingdom - RecruitingNA
Can Personalised Digital Feedback Help Increase Plant Food Intake?
This study looks at whether a special app with personalised tips and recipes can help people aged 18-45 eat more plant-based foods. It hopes to find new ways to improve diet and health.
For: Plant Food IntakeUnited Kingdom - Active not recruitingPHASE2, PHASE3
A Clinical Trial Evaluating the Safety and Efficacy of a Single Subretinal Injection of AGTC-501 in Participants With XLRP
This study checks a new gene therapy, AGTC-501, for young men with an eye condition called X-linked retinitis pigmentosa (XLRP). It aims to see if it's safe and helps improve their eyesight, comparing two doses to an untreated group.
For: X-Linked Retinitis PigmentosaUnited States · Australia · Canada