- Active not recruitingPHASE3
A Study Evaluating the Efficacy and Safety of Crovalimab Versus Eculizumab in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) Not Previously Treated With Complement Inhibitors
This study compares two medicines, crovalimab and eculizumab, for a rare blood condition called PNH. It's for people who haven't tried these types of medicines before, checking if crovalimab works as well and is as safe as eculizumab.
For: Paroxysmal Nocturnal HemoglobinuriaArgentina · Brazil · China - Active not recruitingPHASE1, PHASE2
Study to Assess Safety, Efficacy, Pharmacokinetics, and Pharmacodynamics of Crovalimab in Healthy Volunteers and Participants With Paroxysmal Nocturnal Hemoglobinuria
This study is testing a new medicine called crovalimab for a rare blood condition called PNH. It aims to see if it's safe, how it works in the body, and if it helps people with PNH. We're looking at healthy volunteers first, then people with PNH.
For: Paroxysmal Hemoglobinuria, NocturnalFrance · Germany · Hungary - Active not recruitingPHASE3
A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Crovalimab Versus Eculizumab in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) Currently Treated With Complement Inhibitors
This study compares a new medicine, crovalimab, to an existing one, eculizumab, for people with a rare blood condition called PNH. It's looking at how safe and effective crovalimab is in patients already receiving similar treatments.
For: Paroxysmal Nocturnal HemoglobinuriaUnited States · Belgium · Brazil