- Active not recruitingPHASE3
Trial Comparing Irradiation Plus Long Term Adjuvant Androgen Deprivation With GnRH Antagonist Versus GnRH Agonist Plus Flare Protection in Patients With Very High Risk Localized or Locally Advanced Prostate Cancer
This study looks at treating advanced prostate cancer with radiation and hormone therapy. It compares two types of hormone therapy to see which is better at stopping the cancer from growing, spreading, or coming back.
For: Prostate CancerBelgium · Denmark · France - Active not recruitingPHASE2
Comparison of HT Concomitant With RT vs RT Alone in Patients With a Detectable PSA After Prostatectomy
This study compares two treatments for prostate cancer after surgery: hormone therapy plus radiotherapy, or radiotherapy alone. It aims to see which is better at preventing the cancer from returning for men whose PSA levels are rising after an operation.
For: Adenocarcinoma of ProstateFrance - Active not recruitingPHASE3
Two Studies for Patients With Unfavorable Intermediate Risk Prostate Cancer Testing Less Intense Treatment for Patients With a Low Gene Risk Score and Testing a More Intense Treatment for Patients With a Higher Gene Risk Score, The Guidance Trial
This study looks at new ways to treat prostate cancer that hasn't spread but is at medium risk of doing so. It uses a gene test to decide if less or more intense treatment might be better, hoping to reduce side effects or improve outcomes.
For: Prostate AdenocarcinomaUnited States · Canada - Not yet recruitingPHASE2
Study of Radiation Therapy in Combination With Darolutamide + Degarelix in Intermediate Risk Prostate Cancer
This study looks at treating intermediate-risk prostate cancer with radiation and a new hormone therapy. It aims to see if adding the hormone therapy package (darolutamide + degarelix) works better than radiation alone, especially for certain men.
For: Prostate CancerCanada