- Not yet recruitingPHASE2
Long-Term Extension Study in Participants With Duchenne Muscular Dystrophy Amenable to Exon Skipping to Evaluate the Safety and Efficacy of Endosomal Escape Vehicle Phosphorodiamidate Morpholino Oligomer Platform Products (ELEVATE-LTE)
This study looks at new trial medicines, ENTR-601-44 and ENTR-601-45, for boys and young men with Duchenne Muscular Dystrophy (DMD). It checks their long-term safety and how well they work to improve muscle health.
For: Duchenne Muscular Dystrophy (DMD)Belgium · Italy · Netherlands - RecruitingPHASE1, PHASE2
A Study in Participants With Duchenne Muscular Dystrophy Amenable to Exon 45 Skipping to Evaluate the Safety and Efficacy of ENTR-601-45
This study looks at a new medicine, ENTR-601-45, for boys aged 4-20 with Duchenne muscular dystrophy (DMD) where skipping exon 45 is possible. We want to see if it's safe, what side effects it might have, and if it could help. It involves regular clinic visits and infusions.
For: Duchenne Muscular Dystrophy (DMD)Belgium · Italy · Netherlands - RecruitingPhase I/II
A 2-part, randomized, double-blind, placebo-controlled study in participants with Duchenne muscular dystrophy amenable to exon 45 skipping to evaluate the safety and efficacy of ENTR-601-45 (ELEVATE-45)
This study, ELEVATE-45, is testing a new medicine called ENTR-601-45 for Duchenne muscular dystrophy (DMD). It aims to see if it's safe, what side effects it has, and if it helps by increasing a muscle-building protein called dystrophin in boys and young men aged 4-20.
For: Duchenne muscular dystrophyUnited Kingdom · England · Belgium