Experimental Treatment: one course Rituximab/HD-Methotrexate, two courses of MATRix clinical trials

OptiMATe: De-escalated Induction Treatment in Primary CNS Lymphoma

This study looks at a new, less intense treatment for a type of brain lymphoma called Primary CNS Lymphoma. Researchers want to see if this gentler treatment works as well as, or better than, the standard, stronger treatment.