- Active not recruitingPHASE1
A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Mosunetuzumab or Glofitamab in Combination With CC-220 and/or CC-99282 in Participants With B-Cell Non-Hodgkin Lymphoma
This study is testing new combinations of medicines for a type of blood cancer called Non-Hodgkin Lymphoma. It aims to see how safe and effective these new treatments are, and how the body handles them. It's for people whose cancer hasn't responded well to previous treatments.
For: Non-Hodgkin LymphomaUnited States · Israel · Italy - RecruitingPHASE1, PHASE2
A Study to Assess Change in Disease Activity and Adverse Events (AE)s in Adult Participants With Multiple Myeloma Receiving T Cell Engaging Bi/Tri-specific Antibodies Intravenously (IV)/Subcutaneously (SC) Alone or in Combinations
This study is testing a new drug called Etentamig for adults with multiple myeloma, a type of blood cancer. Researchers want to see if it's safe and effective when given alone or with other common treatments to help manage the disease.
For: Multiple MyelomaUnited States · Australia · Israel - RecruitingPHASE1
A Study to Learn About the Effects of the Combination of Elranatamab (PF-06863135) and Iberdomide in Patients With Relapsed or Refractory Multiple Myeloma (MagnetisMM-30)
This study is looking at an experimental treatment for multiple myeloma that has come back or hasn't responded to other treatments. It combines two medicines, elranatamab and iberdomide, to see how safe and effective they are together in adults.
For: Multiple MyelomaUnited States · Australia · Canada - Active not recruitingPHASE3
Open-label Study Comparing Iberdomide, Daratumumab and Dexamethasone (IberDd) Versus Daratumumab, Bortezomib, and Dexamethasone (DVd) in Participants With Relapsed or Refractory Multiple Myeloma (RRMM)
This study compares two treatments for multiple myeloma that has come back or not responded to previous therapy. It aims to see if a new combination, IberDd, works better and is safer than a standard combination, DVd, for patients in the UK.
For: Multiple MyelomaUnited States · Argentina · Australia - RecruitingPHASE3
Iberdomide vs. Iberdomide Plus Isatuximab Maintenance Therapy Post ASCT in Newly Diagnosed Multiple Myeloma
This study compares two treatments for multiple myeloma: iberdomide alone versus iberdomide plus isatuximab. It looks at how well these treatments reduce leftover cancer cells after a stem cell transplant, aiming to find the best long-term care.
For: Multiple MyelomaAustria · Germany - RecruitingPHASE1
Study of Intravenously (IV) Infused Etentamig in Combination With an Oral Cereblon E3 Ligase Modulatory Drug (CELMoD) Agent Assessing Adverse Events and Change in Disease Activity in Adult Participants With Relapsed or Refractory Multiple Myeloma
This study looks at a new drug, etentamig, combined with iberdomide, for adults with multiple myeloma that has come back or not responded to previous treatments. It aims to see how safe the combination is and if it helps control the disease.
For: Multiple MyelomaUnited States · Australia · Canada - RecruitingPHASE2
Isatuximab and Iberdomide as Immunotherapy for High Risk in Smouldering Myeloma
This study looks at a new drug combination (Isatuximab, Iberdomide, and Dexamethasone) for people with early-stage, "smouldering" myeloma that has a higher chance of turning into active myeloma. It aims to see if these drugs can stop or slow down the disease's progression.
For: Smouldering MyelomaUnited Kingdom - Active not recruitingPHASE3
A Study to Compare Iberdomide Maintenance Versus Lenalidomide Maintenance Therapy Following Autologous Stem Cell Transplant in Participants With Newly Diagnosed Multiple Myeloma
This study compares two treatments, Iberdomide and Lenalidomide, after a stem cell transplant for multiple myeloma. It aims to find out which one works better at keeping the cancer under control following initial treatment.
For: Multiple MyelomaUnited States · Argentina · Australia