- Active not recruitingPHASE1
A Study of LOXO-783 in Patients With Breast Cancer/Other Solid Tumors
This study is looking into a new medicine, LOXO-783, for breast cancer and other solid tumours with a specific gene change (PIK3CA). It aims to understand if the medicine is safe, what side effects it has, and how well it works.
For: Breast CancerUnited States · Australia · Belgium - Active not recruitingPHASE3
A Study of Imlunestrant Versus Standard Endocrine Therapy in Participants With Early Breast Cancer
This study looks at a new drug, imlunestrant, for early breast cancer. It compares it to standard hormone treatments like tamoxifen, anastrozole, letrozole, and exemestane. The goal is to see if imlunestrant works better for patients whose cancer is at higher risk of returning.
For: Breast NeoplasmsUnited States · Argentina · Australia - Active not recruitingPHASE3
A Study of Imlunestrant, Investigator's Choice of Endocrine Therapy, and Imlunestrant Plus Abemaciclib in Participants With ER+, HER2- Advanced Breast Cancer
This study for advanced ER+, HER2- breast cancer tests a new drug called imlunestrant. Researchers want to see if it works better than standard hormone therapy, and if adding abemaciclib helps even more. It aims to find better treatments for this common type of breast cancer.
For: Breast Neoplasms · Neoplasm MetastasisUnited States · Argentina · Australia - Not yet recruitingPHASE2
A Study of Imlunestrant (LY3484356) in Premenopausal Women With Estrogen Receptor-Positive (ER+) Human Epidermal Growth Factor Receptor 2 Negative (HER2-) Early Breast Cancer
This study looks at a new drug, imlunestrant, for premenopausal women with a common type of early breast cancer. Researchers want to see how it affects cancer cells and the ovaries, comparing it to an existing treatment called tamoxifen. It’s for women whose breast cancer is sensitive to hormones.
For: Breast NeoplasmsUnited States · Belgium · France