infusional 5-FU/FA "de Gramont" (adjuvant) clinical trials

Preoperative FOLFOX Versus Postoperative Risk-adapted Chemotherapy in Patients With Locally Advanced Rectal Cancer

This study compares different ways to treat advanced rectal cancer. It looks at giving chemotherapy before surgery versus after, to see which approach works best for certain patients, aiming to reduce the cancer coming back in other parts of the body.