- AuthorisedTherapeutic confirmatory (Phase III)
A Randomized, Active-Controlled, Double-blind, Multicenter, Phase 3 Clinical Study of Ivonescimab in Combination with FOLFOX versus Bevacizumab in Combination with FOLFOX for the First-line Treatment of Metastatic Colorectal Cancer (HARMONi-GI3)
This study is looking at a new treatment called ivonescimab, given with standard chemotherapy (FOLFOX), for bowel cancer that has spread. We compare it to another treatment (bevacizumab) also with FOLFOX, to see which works best at stopping the cancer from growing.
For: Metastatic colorectal cancerBelgium · Italy · Spain - RecruitingPHASE2
Testing Ivonescimab Versus FOLFOX in Advanced Biliary Tract Cancer Patients
This study tests a new medicine called ivonescimab for advanced bile duct cancer. It's for patients who previously took part in the SAFIR-ABC10 study but didn't get the experimental treatment, and whose cancer has progressed after initial chemotherapy. We want to see if ivonescimab works better than standard chemotherapy.
For: Biliary Tract CancerFrance · United Kingdom