- RecruitingPHASE3
Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of KarXT in Subjects With Psychosis Associated With Alzheimer's Disease (ADEPT-3)
This study looks at the long-term safety of a new medicine, KarXT, for people with changes in their thoughts and feelings due to Alzheimer's disease. Participants have already taken part in similar studies and will continue to be monitored for about a year.
For: Psychosis Associated With Alzheimer's DiseaseUnited States · Argentina · Belgium - RecruitingPHASE3
A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-2)
This study is testing a new medicine, KarXT, for people aged 55-90 who have Alzheimer's disease and also experience psychosis (like seeing or hearing things that aren't there, or having strong untrue beliefs). It aims to see if KarXT can help reduce these symptoms and is safe to use.
For: Psychosis Associated With Alzheimer's DiseaseUnited States · Belgium · Canada - RecruitingPHASE3
A Study to Evaluate Safety and Efficacy of KarXT + KarX-EC as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-5)
This study is looking at a new treatment called KarXT + KarX-EC for psychosis, which can affect people with Alzheimer's disease. Researchers want to see if this treatment is safe and helps reduce psychotic symptoms like hallucinations or delusions in individuals aged 55 to 90.
For: Alzheimer Disease · PsychosisUnited States · Australia · Canada - RecruitingPHASE3
A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in Alzheimer's Disease (ADAGIO-3)
This study looks at a new medicine for agitation in people with Alzheimer's. It aims to see if an experimental drug, given as capsules, is safe and works well over a long time for those who've been in similar studies before.
For: Alzheimer Disease · AgitationUnited States · Argentina · Brazil - RecruitingPHASE3
A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)
This study is looking into a new treatment called KarXT + KarX-EC for people with mild to moderate Alzheimer's disease. Researchers want to see if it can help improve memory and thinking, and if it's safe to use.
For: Alzheimer's DiseaseUnited States · Argentina · Australia - RecruitingPHASE3
A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease
This study is looking at a new medicine called KarXT + KarX-EC to see if it can help improve memory and thinking skills in people with Alzheimer's disease. It also checks if the medicine is safe to use. Some people will get the active medicine, others a dummy pill.
For: Alzheimer's DiseaseUnited States · Argentina · Australia - Not yet recruitingPHASE3
A Study of KarXT + KarX-EC for Treatment of Irritability in Children and Adolescents With Autism Spectrum Disorder
This study is looking at a new medication called KarXT combined with KarX-EC to help children and teenagers with autism who experience a lot of irritability. The aim is to see if this combination can make them feel less irritable.
For: Irritability Associated With Autism Spectrum DisorderUnited States · France · Germany - RecruitingPHASE3
A Study to Evaluate the Long-term Safety and Tolerability of KarXT and KarX-EC for the Treatment of Schizophrenia and Autism-Related Irritability in Adolescents, Respectively
This study looks at a medicine called KarXT for young people aged 5 to 17. It checks how safe and tolerable it is over a long time for schizophrenia and irritability linked to autism. It's for those who have already started treatment in previous related studies.
For: Schizophrenia · Autism-Related IrritabilityUnited States · Argentina · Canada - RecruitingPHASE3
A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-1)
This study is looking into a new medication called KarXT for people with memory problems like Alzheimer's who also experience psychosis. It compares KarXT to a dummy pill to see if it can prevent these symptoms from returning and if it's safe to use.
For: Psychosis Associated With Alzheimer's DiseaseUnited States · Bulgaria · Croatia