Ketamine hydrochloride clinical trials
6 indexed studies · 4 currently recruiting
- CompletedNot Applicable
Reward emotion learning and ketamine study
This Oxford University study explores how ketamine affects learning and memory in healthy volunteers. Ketamine can improve depression quickly, but scientists need to know how it changes brain activity. Participants will complete computer tasks, receive a single dose of ketamine or a dummy treatment, and have a brain scan.
For: Cognitive effects of ketamine on healthy volunteersUnited Kingdom · England - RecruitingPHASE3
The Effect of a Six Week Intensified Pharmacological Treatment for Major Depressive Disorder Compared to Treatment as Usual in Subjects Who Had a First-time Treatment Failure on Their First-line Treatment.
This study looks into new ways to treat severe depression when first treatments haven't worked well. It compares an intensive use of esketamine (a type of ketamine) with usual care, aiming to find better and faster relief for people struggling with depression.
For: Major Depressive Disorder · Treatment Resistant DepressionAustria · Germany · Greece - RecruitingNA
Dexmedetomidine and Ketamine in VATS Surgery
This study looks at how combining two medicines, ketamine and dexmedetomidine, can reduce pain after lung surgery (VATS). The goal is to lower the amount of strong pain relievers (like morphine) needed, which can cause unwanted side effects.
For: Postoperative Pain · Opioid UseCanada - Not yet recruitingPHASE3
Ketamine Sedation in the ICU (KANINE) RCT
This study looks at adding a drug called ketamine to usual care for very sick patients in intensive care who need help breathing. It aims to see if ketamine is safe and helpful, potentially reducing how long patients need a breathing machine and improving their recovery.
For: Mechanical Ventilation · Critically Ill Intensive Care Unit PatientsCanada - RecruitingPHASE2, PHASE3
Understanding and Treating Suicidal Ideation With Ketamine
This study looks at whether ketamine can quickly help people with severe depression who are having thoughts of suicide. Researchers will also use brain scans and talks to understand how ketamine helps and what changes in the brain and mind.
For: Suicidal Ideation · Major Depressive Disorder (MDD)Canada - AuthorisedTherapeutic exploratory (Phase II)
Ketamine maintenance treatment for depression: A multicenter open-label randomized controlled trial
This study looks into using ketamine to help people with severe depression. It aims to see how long people stay well after ketamine treatment and whether it can prevent their depression from returning. Researchers are also checking for any side effects.
For: Major Depression Disorder (MDD)Norway