- AuthorisedHuman Pharmacology (Phase I)- Other
A Phase 1B, Open-Label Study of Mirdametinib in Infants and Toddlers with Neurofibromatosis Type 1 associated Plexiform Neurofibromas
This study is looking at a new medicine called Mirdametinib for babies and toddlers with a condition called Neurofibromatosis Type 1 (NF1). It aims to check if the medicine is safe and how it affects benign tumours called plexiform neurofibromas.
For: Neurofibromatosis Type 1 (NF1) Associated Plexiform Neurofibromas (PN)Spain · Germany - RecruitingPHASE1, PHASE2
Phase 1/2 Study of Mirdametinib + Vinblastine for Newly Diagnosed/Previously Untreated PLGG + Activation of MAPK
This study looks at a new drug, mirdametinib, combined with traditional chemotherapy (vinblastine) for children and young people aged 2-25 with a specific type of brain tumour called low-grade glioma. We want to see if this combination works safely and effectively.
For: Pediatric Low-grade GliomaCanada