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Mitapivat-matching placebo clinical trials
3 indexed studies · 0 currently recruiting
- Active not recruitingPHASE2, PHASE3
A Study Evaluating the Efficacy and Safety of Mitapivat (AG-348) in Participants With Sickle Cell Disease (RISE UP)
This study is looking at a new medicine called mitapivat for sickle cell disease. It aims to find the right dose and see if it helps increase healthy red blood cells and reduce painful crises.
For: Sickle Cell DiseaseUnited States · Belgium · Brazil - Active not recruitingPHASE3
A Study to Evaluate the Efficacy and Safety of Mitapivat in Pediatric Participants With Pyruvate Kinase Deficiency (PKD) Who Are Not Regularly Transfused, Followed by a 5-Year Extension Period
This study is for children aged 1 to 17 with a blood condition called Pyruvate Kinase Deficiency (PKD) who don't regularly need blood transfusions. It's testing a new medicine called mitapivat to see if it's safe and effective, compared to a dummy medicine.
For: Pediatric Pyruvate Kinase Deficiency · Pediatric Hemolytic AnemiaUnited States · Canada · France - Active not recruitingPHASE3
A Study to Evaluate the Efficacy and Safety of Mitapivat in Pediatric Participants With Pyruvate Kinase Deficiency (PKD) Who Are Regularly Transfused, Followed by a 5-Year Extension Period
This study is looking at a new medicine called Mitapivat for children with a rare blood disorder called Pyruvate Kinase Deficiency (PKD). It aims to see if Mitapivat can help children who need regular blood transfusions, compared to a dummy medicine.
For: Pediatric Pyruvate Kinase Deficiency · Pediatric Hemolytic AnemiaUnited States · Canada · Czechia