- Active not recruitingPHASE3
International Randomised Phase III Clinical Trial in Children With Acute Myeloid Leukaemia
This study looks at new ways to treat children with a type of blood cancer called Acute Myeloid Leukaemia (AML). It compares different chemotherapy drugs, including a drug called gemtuzumab ozogamicin, and different types of stem cell transplants to find the most effective and safest treatments for young patients.
For: Acute Myeloid LeukaemiaAustralia · France · Ireland - Active not recruitingPHASE2
A Global Study of Midostaurin in Combination With Chemotherapy to Evaluate Safety, Efficacy and Pharmacokinetics in Newly Diagnosed Pediatric Patients With FLT3 Mutated AML
This study is testing a new combination of treatments for children and teenagers with a certain type of acute myeloid leukemia (FLT3-mutated AML). It combines a drug called midostaurin with standard chemotherapy to see if it's safe and effective for these patients.
For: FLT3-mutated Acute Myeloid LeukemiaCzechia · Germany · Italy - Active not recruitingPHASE1, PHASE2
Total Therapy for Infants With Acute Lymphoblastic Leukemia (ALL) I
This study looks at new drug combinations for babies with a type of blood cancer called acute lymphoblastic leukaemia (ALL). It explores how well new drugs, bortezomib and vorinostat, work with standard treatments and checks for any side effects, aiming to improve treatment outcomes for these infants.
For: Acute Lymphoblastic LeukemiaUnited States · Canada