- RecruitingPHASE4
Nirogacestat in Premenopausal Females With Desmoid Tumor/Aggressive Fibromatosis (DT/AF)
This study looks at a medicine called nirogacestat for women with desmoid tumours. It aims to understand how the medicine affects their ovaries and if it helps treat their tumour, while also checking for any side effects.
For: Desmoid Tumor · Aggressive FibromatosisBelgium · Germany · Italy - Active not recruitingPHASE1
A Study of Teclistamab With Other Anticancer Therapies in Participants With Multiple Myeloma
This study is testing a new medicine called teclistamab, combined with other treatments, for people with multiple myeloma. Scientists want to find the safest and best doses of these combinations to treat the disease effectively.
For: Multiple MyelomaUnited States · Australia · Belgium - Active not recruitingPHASE1, PHASE2
Sub-study of Belantamab Mafodotin (GSK2857916) in Combination With Nirogacestat, Lenalidomide, and Dexamethasone in Participants With RRMM
This study is testing a new combination of medicines for multiple myeloma, a type of blood cancer. It aims to find the safest and most effective dose of Belantamab mafodotin, Nirogacestat, Lenalidomide, and Dexamethasone for people whose myeloma has returned or not responded to previous treatments.
For: Multiple MyelomaUnited States · Brazil · Canada - Active not recruitingPHASE1, PHASE2
Sub-study of Belantamab Mafodotin (GSK2857916) in Combination With Nirogacestat in Participants With RRMM
This study is looking at a new combination of two drugs, Belantamab Mafodotin and Nirogacestat, for people with multiple myeloma that has come back or not responded to previous treatments. The main goal is to find a safe dose and see how well it works.
For: Multiple MyelomaUnited States · Australia · Canada