placebo stimulation then active stimulation clinical trials

Efficacy of Non-invasive Vagus Nerve Stimulation for Axial Spondyloarthritis Resistant to Biotherapies

This study looks at whether a gentle electrical stimulation of a nerve in the ear, called Vagus Nerve Stimulation (VNS), can help people with a type of arthritis called axial spondyloarthritis that hasn't improved with other strong medicines.