- RecruitingPHASE3
A Study of Pitolisant in Patients With Prader-Willi Syndrome
This study is testing a medication called Pitolisant for people aged 6 and over with Prader-Willi syndrome. It aims to see if it helps with excessive sleepiness and other behaviors, compared to a dummy pill.
For: Prader-Willi SyndromeUnited States · Australia · Belgium - Active not recruitingPHASE3
Efficacy and Safety Studies of Frexalimab (SAR441344) in Adults With Relapsing Forms of Multiple Sclerosis
This study is looking at a new medicine called frexalimab for people aged 18-55 with certain types of Multiple Sclerosis (MS). It compares frexalimab to an existing MS medicine, teriflunomide, to see how well it stops MS relapses and if it's safe.
For: Multiple SclerosisUnited States · Argentina · Austria - RecruitingPHASE2, PHASE3
Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)
This study is looking at a new medicine called vericiguat for children and young people aged 29 days to 17 years with heart failure. We want to see if it can improve their heart health compared to a dummy medicine.
For: Heart Failure · Left Ventricular Systolic DysfunctionUnited States · Belgium · Brazil - Active not recruitingPHASE4
A Study of Two Different Doses of Cabozantinib (XL184) in Progressive, Metastatic Medullary Thyroid Cancer
This study looks at two different doses of a drug called cabozantinib for a type of thyroid cancer called medullary thyroid cancer (MTC) that has spread and is getting worse. We want to see if a lower dose works just as well with fewer side effects.
For: Medullary Thyroid CancerAustralia · Canada · Croatia - RecruitingPHASE2, PHASE3
Study of Dapansutrile Tablets in Subjects With an Acute Gout Flare
This study is looking into a new tablet called dapansutrile to see if it can help people having a painful gout attack. It compares the new tablet with a dummy tablet to check how well it works and if it's safe.
For: Acute Gout Flare · Gout Attack · Gout FlareUnited States · France · Israel