- RecruitingNot Applicable
Sleep Blinding Psilocybin, a feasibility study: Examining if participants can tell if they received psilocybin or a placebo when medication is given to act in sleep
This study explores a new way to test psilocybin (from 'magic mushrooms') for depression by giving it to people while they sleep. This helps researchers understand how it works without participants knowing if they received the drug or a dummy pill.
For: DepressionUnited Kingdom · England - Active not recruitingNA
Psilocybin in Functional Neurological Disorder
This study looks at how a single dose of psilocybin (from magic mushrooms), given with support, affects the brains of people with Functional Neurological Disorder (FND). We want to see if it changes certain brain activity.
For: Functional Neurological DisorderUnited Kingdom - Active not recruitingPHASE3
Efficacy, Safety, and Tolerability of Two Administrations of COMP360 in Participants With TRD
This study is looking at a new treatment called COMP360 (which contains psilocybin) for people with depression that hasn't improved with other treatments. Researchers want to see if it helps reduce depression symptoms and is safe, with participants receiving two doses alongside support.
For: Treatment Resistant DepressionUnited States · Canada · Czechia - RecruitingPHASE2
Psilocybin-Assisted Psychotherapy for Alcohol Use Disorder
This study is looking into whether a single dose of a substance called psilocybin, alongside therapy, can help people with alcohol use disorder reduce their heavy drinking. They want to see if it makes a real difference.
For: Alcohol Use Disorder · AlcoholismCanada - Not yet recruitingPHASE2
Evaluating the Role of Psilocybin Monitors in Psilocybin Therapy for Treatment Resistant Depression
This study is looking at how having a helper (a 'monitor') with you affects psilocybin therapy for severe depression that hasn't responded to other treatments. Psilocybin comes from 'magic mushrooms' and is given with talking support.
For: Treatment-Resistant DepressionCanada - Not yet recruitingPHASE2
Psilocybin-assisted Therapy for Post-Traumatic Stress Disorder in Survivors of Intimate Partner Violence
This study looks at how a specific treatment using psilocybin, given with a type of therapy called ACT, might help adults aged 18-65 who developed PTSD after experiencing domestic abuse. It aims to see if this treatment can reduce their PTSD symptoms.
For: Post Traumatic Stress Disorder PTSD · Intimate Partner Violence (IPV)Canada - RecruitingPHASE2
Psilocybin for Enhanced Analgesia in Chronic nEuropathic PAIN
This study is looking into whether psilocybin, found in 'magic mushrooms', could help people with long-term nerve pain. It's a small, early study to see if it's safe and practical to do a much bigger one later on. Researchers hope to find new ways to manage chronic pain.
For: Chronic Neuropathic Pain · Pain ManagementCanada - RecruitingPHASE1
Treatment of Persisting Symptoms After Concussion With Psilocybin Assisted Therapy
This study is looking at whether a treatment combining psilocybin (a natural substance) with talking therapy can help adults (aged 18-65) who have ongoing symptoms after a concussion. It checks if it's safe, how well it works, and if people find it manageable.
For: Persisting Symptoms After ConcussionCanada