psilocybin (25 mg) clinical trials
4 indexed studies · 4 currently recruiting
- Not yet recruitingPHASE3
Psilocybin-Assisted Therapy for Treatment-Resistant Depression in Bipolar II Disorder
This study looks into using a guided therapy with psilocybin (a compound from magic mushrooms) for people with Bipolar II Depression who haven't found other treatments helpful. We're testing if a single dose of psilocybin works better than a very low dose, alongside support from therapists.
For: Bipolar II DepressionCanada - RecruitingPHASE2
Treatment With Psilocybin for Chronic Neuropathic Pain and Depression (TRANSCEND)
This study is exploring if a single dose of psilocybin, a compound from 'magic mushrooms,' could help people aged 18-65 with tough-to-treat depression and ongoing nerve pain. Researchers want to see if it's safe, and if it makes a difference to their symptoms.
For: Treatment Resistant Depression · Chronic PainCanada - RecruitingPHASE2
Imaging the Effects of Serotonin 2A Receptor Modulation on Synaptic Density in Treatment-resistant Depression (SYNVEST)
This study looks at how psilocybin, found in 'magic mushrooms', might help people with depression that hasn't responded to other treatments. We'll use special scans to see if psilocybin changes brain connections and if this helps relieve depression.
For: Treatment Resistant DepressionCanada - Not yet recruitingPHASE2
Psilocybin-assisted Therapy for Comorbid Major Depressive Disorder and Alcohol Use Disorder
This study looks at how safe and effective psilocybin-assisted therapy is for people experiencing both depression and alcohol problems. Researchers want to see if it helps and if it has any serious side effects compared to a placebo.
For: Major Depressive Disorder (MDD) · Alcohol Use Disorder (AUD)Canada