replaced in the PLACEBO formulation with the same amount of Microcrystalline cellulose, one of the clinical trials

EFFECTS OF SAFINAMIDE VERSUS PLACEBO ON PAIN IN PATIENTS WITH PARKINSON’S DISEASE WITH MOTOR FLUCTUATIONS: A RANDOMIZED, CONTROLLED, DOUBLE-BLIND CLINICAL TRIAL. Protocol code: SAVE PAIN 2025

This study is looking at whether a drug called safinamide can help reduce pain in people with Parkinson's disease who experience 'motor fluctuations' – when their symptoms change throughout the day. It compares safinamide to a dummy pill to see if it makes a difference.