- Active not recruiting
High Gastrointestinal Bleed Risk Outcomes in Patients With Non-valvular Atrial Fibrillation (NVAF) in France
This study looks back at French health records to understand how different blood-thinning medicines affect people with an irregular heartbeat (atrial fibrillation) who are at higher risk of stomach bleeding. It compares older medicines like warfarin with newer ones to see how safe and effective they are.
For: Atrial FibrillationUnited Kingdom - Active not recruiting
Anticoagulation in Patients With Venous Thromboembolism and Cancer
This study looks back at patient records to understand how different blood-thinning medicines work for people with cancer who have also had blood clots. It compares medicines like Apixaban, Rivaroxaban, and Dabigatran to see which are most effective and safe.
For: Neoplasms · EmbolismUnited Kingdom - RecruitingPHASE3
Thromboprophylaxis in Lower Limb Immobilisation
This study looks at new ways to prevent blood clots after a leg injury treated with a cast or splint. It compares injections with tablets and also checks if medication helps those at lower risk of clots. The goal is to find safer and more effective options.
For: Thrombosis · Injury LegUnited Kingdom - RecruitingPHASE4
THRomboprophylaxis in Individuals Undergoing Superficial endoVEnous Treatment (THRIVE)
This study looks at whether blood-thinning medicines can help prevent blood clots after common varicose vein operations. It aims to see if giving these medicines after keyhole procedures for varicose veins is a good idea to keep you safe.
For: Venous Thromboembolism · Varicose VeinsUnited Kingdom - RecruitingPHASE4
Dabigatran vs. Oral Anti-Xa Inhibitors in S. Aureus Bacteremia
This study compares different blood thinners (Dabigatran vs. Apixaban, Edoxaban, or Rivaroxaban) in people with a serious স্টাফ infection (S. aureus bacteremia). We want to see if switching to dabigatran, which might fight the infection, improves outcomes for patients already taking blood thinners.
For: Staphylococcus Aureus Endocarditis · Staphylococcus Aureus Septicemia · Staphylococcus Aureus BacteremiaCanada - RecruitingPHASE4
Clinical Surveillance vs. Anticoagulation for Low-risk Patients With Isolated Subsegmental Pulmonary Embolism
This study looks at the best way to treat small blood clots in the lungs (isolated subsegmental pulmonary embolism) in people at low risk. It compares watching carefully without treatment to giving blood-thinning medicine to reduce bleeding risks.
For: Pulmonary Embolism · Embolism · Embolism and ThrombosisBelgium · Canada · France - Active not recruitingPHASE1
A Study to Investigate Andexanet Dosing and the Interaction Between Andexanet and Subsequent Enoxaparin in Healthy Participants
This study is testing a new medicine called Andexanet. It's for healthy people aged 18 to 55. We want to see how Andexanet works with common blood thinners like Rivaroxaban and Apixaban, and if it affects another blood thinner called Enoxaparin. This helps doctors understand how to use Andexanet safely.
For: Healthy ParticipantsGermany · United Kingdom