- Active not recruitingPHASE2
A Study to Evaluate RO7204239 in Participants With Facioscapulohumeral Muscular Dystrophy
This study is looking into a new medication called RO7204239 for adults with Facioscapulohumeral Muscular Dystrophy (FSHD). It aims to see how safe and effective the medication is, and how it affects the body.
For: Facioscapulohumeral Muscular Dystrophy (FSHD)United States · Denmark · Italy - Active not recruitingPHASE1
A Study to Evaluate the Effect of RO7204239 on Insulin Sensitivity and Muscle Composition in Participants With Type 2 Diabetes Mellitus (T2DM) and Overweight or Obesity
This study looks at a new drug, RO7204239, for people with type 2 diabetes who are overweight or have obesity. It aims to see if the drug can improve how the body uses insulin and affects muscle health. This is an early stage study.
For: Type 2 Diabetes Mellitus · Obesity · OverweightGermany - Active not recruitingPHASE2
A Study to Assess Efficacy, Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of RO7204239 in Combination With Tirzepatide in Participants With Obesity or Overweight With At Least One Weight-related Comorbidity
This study looks at a new medicine, RO7204239, combined with an existing medicine, tirzepatide, for adults who are overweight or have obesity. It aims to see if this combination helps with weight loss and is safe for people without diabetes.
For: Obesity · Overweight · Overweight With One Weight Related ComorbidityUnited States · Poland · Spain - Active not recruitingPHASE2, PHASE3
A Study to Investigate the Safety and Efficacy of RO7204239 in Combination With Risdiplam (RO7034067) in Participants With Spinal Muscular Atrophy
This study is looking into a new combination of medicines, RO7204239 and risdiplam, for people with spinal muscular atrophy (SMA). The aim is to see if this combination is safe and helps improve muscle strength and movement.
For: Spinal Muscular Atrophy (SMA)United States · Australia · Belgium