- RecruitingNA
Coronary Sinus Reducer Implantation in Patients With Ischaemia and Non-obstructed Coronary Arteries and Coronary Microvascular Dysfunction.
This study looks at a new device called a Coronary Sinus Reducer for people with chest pain (angina) caused by problems with very small heart blood vessels. It checks if the device is safe and helps improve blood flow to the heart.
For: Refractory Angina · Microvascular Angina · Microvascular Coronary Artery DiseaseUnited Kingdom - RecruitingPHASE2
A Long-term Extension Study of JNJ-81201887 (AAVCAGsCD59) Parent Studies in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)
This study looks at the long-term safety of a new eye treatment, JNJ-81201887, for geographic atrophy, a type of macular degeneration. It checks how people who received this treatment in earlier studies are doing over time.
For: Geographic Atrophy · Macular DegenerationUnited States · Australia · Belgium - Active not recruitingNA
A Study of the ReCor Medical Paradise System in Clinical Hypertension
This study looks at a new ultrasound system, called Paradise®, to treat high blood pressure. It compares this new treatment with a pretend procedure to see how safe and effective it is for people with different types of high blood pressure.
For: Hypertension · Vascular DiseasesUnited States · Belgium · France - RecruitingNA
Efficacy of Balloon Dilation of the Eustachian Tube in Eustachian Tube Dilatory Dysfunction
This study looks into a new way to treat ear problems called Eustachian tube dysfunction. It compares a balloon procedure to a dummy procedure to see if it helps relieve ear pressure and discomfort when other treatments haven't worked.
For: Eustachian Tube Dysfunction · BarotitisCanada - Active not recruitingPHASE2, PHASE3
Efficacy of Intradiscal Injection of BM-MSC in Subjects With Chronic Low Back Pain (LBP) Due to Lumbar Degenerative Disc Disease (DDD) Unresponsive
This study looks at a new stem cell injection for long-lasting lower back pain caused by worn-out spinal discs. It compares this new treatment to a dummy procedure to see if it reduces pain and improves daily life.
For: Recurrent Low Back Pain · Degenerative Disc Disease (DDD)France · Germany · Italy - Active not recruitingNA
ALT-FLOW II Trial of the Edwards APTURE Transcatheter Shunt System
This study looks at a new device for people with heart failure. It wants to see if the Edwards APTURE shunt system can help improve symptoms for those whose hearts pump well but still feel unwell, even with their usual medicines.
For: Heart FailureUnited States · Brazil · Canada