- RecruitingPHASE2
Methods of T Cell Depletion Trial (MoTD)
This study compares different ways to prevent a complication called GvHD after stem cell transplants for various blood cancers. It's looking for the best treatment plan to help patients recover well, using common medicines like Thymoglobulin, Cyclophosphamide, Cyclosporine, Sirolimus, and Mycophenolate Mofetil.
For: Acute Myeloid Leukemia · Acute Lymphoblastic Leukemia · Chronic Myelomonocytic LeukemiaUnited Kingdom - Active not recruitingPHASE1, PHASE2
Phase 1/2 Clinical Trial of PR001 in Infants With Type 2 Gaucher Disease (PROVIDE)
This study is testing a new treatment, LY3884961, for babies with a serious inherited condition called Type 2 Gaucher disease. Researchers want to see if it's safe and effective. It's a long-term study, following babies for up to 5 years.
For: Gaucher Disease, Type 2United States · United Kingdom - RecruitingPHASE2
Nonmyeloablative Stem Cell Transplant in Children With Sickle Cell Disease and a Major ABO-Incompatible Matched Sibling Donor
This study looks into a new way of doing stem cell transplants for children aged 1 to 19 with sickle cell disease. It aims to make this life-changing treatment available to more children, especially if their donor's blood type doesn't perfectly match theirs.
For: Sickle Cell Disease · Stem Cell Transplant Complications · Red Blood Cell DisorderCanada - RecruitingPHASE3
Efficacy and Safety of Sirolimus in Vascular Anomalies That Are Refractory to Standard Care
This study is looking into a medication called Sirolimus for people with vascular malformations (unusual growths of blood vessels) that haven't responded to other treatments. It aims to see how well it works and if it's safe for children and adults.
For: Vascular MalformationsBelgium · France · Germany