Standard of Care (SOC) clinical trials
6 indexed studies · 4 currently recruiting
- RecruitingPHASE3
Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)
This study looks at the long-term safety and effectiveness of a cancer drug called pembrolizumab (and related treatments) for people with advanced cancers. It's for patients who are already receiving these treatments in other studies and want to continue.
For: Solid Tumors · Hematologic MalignanciesUnited States · Argentina · Australia - RecruitingPHASE1, PHASE2
An Open-label Dose Escalation and Expansion, Followed by a Phase II Study of Tulmimetostat (DZR123) and JSB462 (Luxdegalutamide) in Patients With Progressive Metastatic Castrate Resistant Prostate Cancer (mCRPC) (TulmiSTAR-01)
This study looks at new treatments for advanced prostate cancer that has stopped responding to hormone therapy. We're testing a combination of two new drugs, tulmimetostat and JSB462, to see if they are safe and work better than standard care for men with this type of cancer.
For: Progressive Metastatic Castrate Resistant Prostate CancerUnited States · Australia · Canada - Not yet recruitingNA
Personalised Pharmacometabolomic-guided Strategy Trial to Optimise Treatment for Hypertension
This study explores a 'smart approach' to choosing high blood pressure medication. By analysing blood tests and clinical information, doctors aim to find the best treatment for you, potentially reducing side effects and improving blood pressure control.
For: HypertensionGermany · Netherlands · Spain - Active not recruitingPHASE1, PHASE2
A Phase 1/2/3 Study of UX701 Gene Therapy in Adults With Wilson Disease
This study is testing a new gene therapy called UX701 for adults with Wilson disease. It aims to see if UX701 is safe, works well to help control copper levels, and to find the best dose. It will compare UX701 to usual treatments.
For: Wilson DiseaseUnited States · Portugal · Spain - Not yet recruitingNA
A Study Testing a New Heart Scan Method to Improve Pacemaker Treatment for Heart Failure
This study looks at a new heart scan measurement, called EF1, to see if it can better predict who will benefit from a pacemaker treatment called Cardiac Resynchronisation Therapy (CRT) for heart failure. We hope this helps more people get the right treatment.
For: Cardiac Resynchronisation Therapy (CRT) · Heart FailureUnited Kingdom - Active not recruitingNA
Post-Marketing Study to Assess the Safety & Efficacy of RenalGuard® Therapy for Prevention CSA-AKI
This study looks at a treatment called RenalGuard Therapy to prevent kidney injury (AKI) after heart surgery. It compares RenalGuard to usual care in patients at higher risk of kidney problems after their operation.
For: AKI - Acute Kidney Injury · Cardiac Surgery Associated - Acute Kidney InjuryBelgium · Germany · Israel