- Active not recruitingPHASE3
Evaluation of Oral Tofacitinib in Children Aged 2 to 17 Years Old Suffering From Moderate to Severe Ulcerative Colitis
This study is looking at a medicine called tofacitinib for children aged 2-17 with a bowel condition called ulcerative colitis. It aims to see how well it works, how safe it is, and how the body uses it, especially if other treatments haven't worked.
For: Ulcerative ColitisUnited States · Australia · Belgium - RecruitingPHASE3
Trial of Sequential Medications AfteR TNFi Failure in Juvenile Idiopathic Arthritis
This study is for children aged 2-17 with a type of arthritis called JIA, who haven't fully responded to their first TNF inhibitor medicine. It compares different existing medicines to find the best next steps for treatment.
For: Polyarticular Course Juvenile Idiopathic Arthritis (JIA)United States · Germany · Italy - RecruitingPHASE4
A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC)
This study looks at combining two medicines, vedolizumab and tofacitinib, for adults with moderate to severe ulcerative colitis. We want to see if this combination helps more than vedolizumab alone, especially for people who haven't responded well to other treatments.
For: Ulcerative ColitisUnited States · Canada