- Active not recruitingPHASE3
DAY101 vs. Standard of Care Chemotherapy in Pediatric Participants With Low-Grade Glioma Requiring First-Line Systemic Therapy (LOGGIC/FIREFLY-2)
This study is for children and young people under 25 with a type of brain tumour called low-grade glioma. It compares a new medicine, tovorafenib, with standard chemotherapy to see which works best and is safest for those needing first-time treatment.
For: Low-grade Glioma · Rapidly Accelerated Fibrosarcoma (RAF) Altered Glioma · Pediatric Low-grade GliomaUnited States · Australia · Austria - RecruitingEARLY_PHASE1
Pilot Study of Vinblastine and Tovorafenib in Pediatric Patients With Recurrent/Progressive RAF Altered Low Grade Gliomas
This study looks at a new combination of two medicines, tovorafenib and vinblastine, for children and young adults (up to 25) with a type of brain tumour called low-grade glioma. It focuses on tumours with specific genetic changes.
For: Low-grade GliomaCanada - RecruitingPHASE2
A Study to Evaluate Tovorafenib in Pediatric and Young Adult Participants With Relapsed or Progressive Low-Grade Glioma and Advance Solid Tumors
This study is looking into a new medicine, Tovorafenib, for children and young adults aged 6 months to 25 years in the UK. It focuses on those with specific types of brain tumours (low-grade glioma) or advanced solid tumours that have come back or gotten worse, especially if they have certain genetic changes.
For: Low-grade Glioma · Advanced Solid TumorUnited States · Australia · Canada