Venetoclax, Venetoclax, Venetoclax, Gazyvaro 1,000 mg concentrate for solution for infusion. clinical trials

HOVON 139 CLL: A prospective, open-label, multicenter randomized phase-II trial to evaluate the efficacy and safety of a sequential regimen of Gazyvaro (obinutuzumab) followed by obinutuzumab and venetoclax, followed by either standard venetoclax maintenance or MRD guided venetoclax maintenance in first-line patients with CLL and unfit for FCR-like regimens. (GIVE trial).

This study looks at new ways to treat chronic lymphocytic leukaemia (CLL). It combines a medicine called obinutuzumab with venetoclax to see if it helps patients who can't have standard chemotherapy. Researchers want to find out how well it works and if it can clear all signs of the cancer.