Zibotentan, Zibotentan, Zibotentan, Zibotentan Placebo, Dapagliflozin Placebo, DAPAGLIFLOZIN clinical trials

A Two Part Phase IIa/b Multicenter, Randomized, Double-Blind, Placebo Controlled, Parallel Group Dose ranging Study to Assess Efficacy, Safety, and Tolerability of the Combination of Zibotentan and Dapagliflozin, and Dapagliflozin Monotherapy Versus Placebo in Participants with Cirrhosis with Features of Portal Hypertension

This study looks at new ways to treat liver scarring (cirrhosis) that causes high pressure in the liver. We are testing a combination of two medicines, Zibotentan and Dapagliflozin, against Dapagliflozin alone or a dummy pill, to see if they can lower this pressure and are safe.