A Pilot Study of the VosCryoTM Breathalyser in Lung Cancer

This study is looking into a new way to help diagnose lung cancer more easily in the future. Lung cancer is a serious illness, and finding it early often means treatments are more effective. However, current ways to diagnose it can sometimes be uncomfortable or involve complicated procedures. Researchers are hoping to find a simpler method.

The study uses a special device called the VosCryoTM breathalyser. It's a bit like a regular breathalyser, but its purpose is to collect tiny samples from your breath. When you breathe out, particularly after a deep breath, your breath contains tiny droplets of fluid from your lungs. These droplets can carry cells and other important information from inside your body. The researchers want to see if this device can collect enough of these cells from people with advanced lung cancer to be useful for testing.

In this study, they will compare breath samples from two groups: people with advanced lung cancer and healthy relatives who do not have cancer. By comparing the samples, they hope to learn if the VosCryoTM breathalyser can pick up differences that show whether someone has lung cancer or not. If successful, this simple breath test could one day become part of how doctors check for lung cancer, potentially making diagnosis quicker and less invasive.', 'eligibility_plain': 'To join this study, you need to be at least 16 years old and be able to understand and sign a consent form. You might be eligible if you have advanced lung cancer (either non-small cell or small cell lung cancer) that has not yet been treated with chemotherapy or radiation. Even if you had early-stage lung cancer that was treated in the past, you might still be able to join. If you have advanced lung cancer that has spread outside the chest, you may still be eligible if your doctor thinks any previous treatments for spread, like radiation to a bone, won't affect the breath sample.

Alternatively, if you are a healthy relative or friend of someone with advanced lung cancer, you could be eligible for the 'control group'. This means you shouldn't have a history of lung cancer or any other type of cancer (unless it was a very common skin cancer or a very early cancer that was completely treated at least two years ago).

Anyone who has a current chest infection or any difficulty giving a breath sample would not be able to take part. Also, if your cancer started somewhere else in your body and has spread to your lungs (rather than being lung cancer itself), you would not be able to participate. You must be able to understand and agree to take part.