A Study to Investigate Safety and Efficacy of Tapinarof Cream, 1% in Participants Ages 3 Months to < 24 Months With Atopic Dermatitis

To join this study, your child needs to be between 3 months and under 2 years old and have a clear diagnosis of eczema. Their eczema should cover more than 5% of their body, and a doctor will need to confirm its severity.

You, as their parent or legal guardian, must be willing to provide permission for your child to take part. You also need to be able to follow all the instructions given by the study team throughout the research period.

There are also some reasons why a child might not be able to join the study. These include having certain other health conditions, like a history of seizures, serious heart problems, or other significant ongoing illnesses. Children who have a weak immune system, current serious infections, or are taking medications that might interfere with the study cream would also not be eligible. If a mother is breastfeeding a child in the study, she also can't be taking certain medications.

If your child takes part in this study, you would bring them to several study visits at a clinic. At these visits, doctors and nurses would check your child's eczema, assess their general health, and record any changes. You would be given either the tapinarof cream or the vehicle cream to apply to your child's skin at home, following specific instructions. The study team would explain exactly how and when to apply the cream. There will be regular check-ups to monitor your child’s progress and safety. The study will involve a set duration of treatment and follow-up, which the study team will explain in detail during the consent process.