RecruitingOBSERVATIONAL

MAIN-IMAGE Registry

This study, called the MAIN-IMAGE Registry, is for people who have been diagnosed with Coronary Artery Disease. This is a condition where the blood vessels supplying your heart become narrowed or blocked. During a heart procedure called a cardiac catheterisation, doctors sometimes use special cameras, called OCT or IVUS, to look inside your heart arteries. This study collects information from these scans. We want to find out if certain features seen in these images can help predict if someone might have future heart problems, like another heart attack, or if their heart disease might get worse over time. By looking at these details, we hope to improve our understanding of heart disease and potentially help doctors provide better care in the future.

At a glance

Status

Recruiting

Sponsor

Goethe University

Enrolment target

500

Start

26 Sep 2023

Estimated completion

26 Sep 2031

Coronary Artery Disease

What is this study about?

This study, called the MAIN-IMAGE Registry, is about understanding Coronary Artery Disease better. Coronary Artery Disease is a common heart condition where the main blood vessels that supply your heart become narrower or get blocked. This can lead to serious problems like chest pain (angina) or even a heart attack. When doctors perform a procedure called a cardiac catheterisation to look at your heart arteries, they sometimes use special tiny cameras called Optical Coherence Tomography (OCT) or Intravascular Ultrasound (IVUS). These cameras create very detailed pictures of the inside of your blood vessels.

The main idea behind this study is to gather information from these detailed heart artery pictures. We want to see if certain patterns or features seen in these images can tell us more about a person's heart disease. For example, can we spot certain things in the pictures that might suggest someone is more likely to have a heart attack in the future, or that their heart condition might get worse over time?

By carefully examining these images and comparing them with what happens to people over time, researchers hope to learn more about how Coronary Artery Disease develops and progresses. This knowledge could eventually help doctors identify people at higher risk of future problems and offer them more tailored treatments or advice, ultimately improving the care for individuals with heart disease.

Key takeaways

This study looks at images from heart procedures.
It aims to understand if certain image details predict future heart problems.
Participation involves no extra tests or appointments for you.
It could help doctors understand heart disease better in the future.
Open to adults over 18 with heart artery disease having a specific scan.

Who may be eligible?

This study is open to adults aged 18 and over, of any gender.

You might be able to take part if you are already having a heart procedure where doctors use special cameras (called OCT) to look inside your heart arteries before any treatment is given.

There are no specific reasons listed that would prevent you from joining, other than not meeting the main requirement mentioned above.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

Are you 18 years old or older?
Are you having a heart procedure (cardiac catheterisation)?
Will you be having an OCT scan during that procedure, before any treatment?
Have you been diagnosed with Coronary Artery Disease?

Answer every question to see your result.

What does participation involve?

If you take part in this study, you won't need to do anything extra. This study simply uses information gathered from scans you would already be having as part of your standard medical care during a heart procedure (cardiac catheterisation). This means there are no additional visits, assessments, medications, or follow-up appointments required specifically for this study. The study looks at pictures taken inside your heart arteries during your procedure.

Potential risks and benefits

Because this study only involves collecting and looking at information from scans you are already having as part of your usual medical care, there are no additional risks directly from participating in the study itself. There are also no direct benefits to you as an individual, but the information collected could help doctors better understand heart disease in the future, potentially leading to improved care for others. You are free to decide not to take part at any point, and this will not affect your medical care.

Locations (2)

Frankfurt University Hospital
Verified postcode
Frankfurt am Main, Germany· Recruiting
Frankfurt University Hospital
Verified postcode
Frankfurt, Germany· Recruiting

Common questions

What is Coronary Artery Disease?

It's a condition where the blood vessels supplying your heart become narrowed or blocked, which can lead to chest pain or a heart attack.

What is a cardiac catheterisation?

It's a procedure where doctors put a thin tube into a blood vessel to look at your heart and arteries, sometimes to treat problems.

What are OCT or IVUS cameras?

These are tiny cameras doctors use during a cardiac catheterisation to get very detailed pictures from inside your heart arteries.

Will I need extra tests for this study?

No, this study only uses information from tests you would already be having as part of your heart care.

Why is this study important?

It helps researchers learn more about warning signs in heart scans that might predict future heart problems, potentially improving care for others.

How to find out more

Lena Seegers, MD

lena.seegers@herz-frankfurt.de +4963016666 Official trial record

Always speak to your GP or specialist before deciding to take part in a study.