A study investigating the safety, absorption, and elimination of NT 0150, a new compound that may potentially be used in the treatment of brain disorders, like Alzheimer’s disease and Parkinson’s disease.
This study is an early research trial, known as a Phase 1 study, testing a new medicine called NT 0150 for the very first time in people. Researchers want to find out how safe the medicine is, what side effects it might cause, and how the human body breaks it down and removes it. NT 0150 is being developed to treat conditions linked to inflammation. This includes brain conditions such as Alzheimer's disease and Parkinson's disease, as well as rare inflammatory illnesses like Cryopyrin-Associated Periodic Syndrome (CAPS). Because this is the first time the drug is given to humans, doctors will closely monitor all participants. The trial is open to adults aged 18 and over. While taking part may not directly cure or treat your condition, it provides vital clues that could lead to new treatments in the future.
At a glance
What is this study about?
This clinical trial is testing a brand-new experimental medicine called NT 0150. It is a 'Phase 1' study, which means it is the very first time the medicine is being given to human volunteers. Before any new medicine can be prescribed by doctors, it must go through strict checks to see how it behaves in the human body.
Researchers are focusing on three main questions: Is the medicine safe? What side effects does it cause? And how does the body absorb, process, and clear it away? NT 0150 is designed to calm down harmful inflammation. Scientists hope it could eventually help treat long-term illnesses, including rare conditions like Cryopyrin-Associated Periodic Syndrome (CAPS) and brain disorders such as Parkinson's or Alzheimer's disease.
Studies like this are crucial because they lay the groundwork for all future medical treatments. By learning how the medicine works in a small group of people under close medical supervision, researchers can work out the safest dose to test in larger studies down the line.
Key takeaways
- Tests a new medicine called NT 0150 in humans for the very first time.
- Aims to check the drug's safety, side effects, and how the body clears it.
- Could help future research into brain conditions and inflammatory diseases.
- Open to adults aged 18 and over who meet strict health criteria.
- Involves regular health monitoring, blood tests, and potential clinic stays.
- Participation is completely voluntary, and you can withdraw at any time.
Who may be eligible?
This trial is open to adults aged 18 and older of any sex. Because this is a Phase 1 trial, the study team has strict guidelines to ensure that taking part is as safe as possible for everyone involved.
Depending on the specific part of the study, researchers may look for healthy adult volunteers, or in some cases, people living with specific inflammatory conditions. The medical team will check your overall health before you can join.
People who are pregnant, breastfeeding, or taking certain medications may not be able to take part. The trial team will review your full medical history and perform health checks to confirm whether the study is suitable for you.
Could this study suit you?
Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.
- I am aged 18 or older.
- I am willing to undergo regular blood and health tests.
- I am available to visit or stay at the trial clinic as needed.
- I can follow instructions regarding medications and lifestyle during the study.
- I am not currently pregnant or planning a pregnancy during the trial.
What does participation involve?
If you take part, you will first attend a screening visit to check your general health through blood tests, urine tests, heart traces (ECGs), and blood pressure checks. If you join, you will be given the study medicine NT 0150, usually as a tablet, capsule, or liquid. You will need to stay at the clinic or visit regularly so doctors can monitor you closely. They will take regular blood samples over several hours or days to measure how quickly your body absorbs and removes the drug. The study team will track your health throughout, and total participation typically lasts from a few days to several weeks, including a final follow-up check.
Potential risks and benefits
Locations (1)
- —UnverifiedNetherlands
Common questions
What is a Phase 1 clinical trial?
A Phase 1 trial is the earliest stage of testing a new drug in humans. Its main goal is to check safety and find the right dose, rather than cure an illness.
Will taking part cure my condition?
No. Because this is a very early safety test, you should not expect any direct improvement in your health or condition.
Do I have to stay overnight at the clinic?
Many Phase 1 studies require short overnight stays so the medical team can run tests and monitor you safely around the clock.
Can I leave the study if I change my mind?
Yes. You can leave the study at any time, for any reason, and your normal healthcare will continue as usual.
Are travel expenses covered?
Phase 1 trials often provide reimbursement for travel expenses and time spent at the clinic. The study team will explain this before you join.
How to find out more
Always speak to your GP or specialist before deciding to take part in a study.
Interested in taking part?
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