Not yet recruitingPHASE2, PHASE3INTERVENTIONAL

Yeast Protein for Muscle Mass

This research study is looking at how two different protein supplements, yeast protein and whey protein, affect muscle growth in healthy adults aged 18 to 35. Many animal-based proteins like whey are known for helping build muscle, but this study wants to see if a more sustainable option, yeast protein, can work just as well. Participants will be randomly assigned to take either yeast protein or whey protein every day for 16 weeks, alongside a resistance training exercise program. The scientists want to find out if yeast protein can lead to similar muscle gains, improved immune function, and a healthier gut, compared to traditional whey protein. This is important for finding effective and environmentally friendlier ways to support muscle health.

At a glance

Status

Not yet recruiting

Phase

PHASE2, PHASE3

Sponsor

University of Alberta

Enrolment target

Start

01 Jul 2026

Estimated completion

01 Jul 2029

Healthy Adult Participants

What is this study about?

This study is investigating how two different protein supplements, yeast protein and whey protein, affect your muscles. We know that getting enough protein is really important for building and repairing muscles, especially when you exercise. Whey protein, which comes from milk, is a popular choice and is known to be very effective. However, the researchers in this study are exploring a newer option: yeast protein. This type of protein is made in a more environmentally friendly way, and it’s thought to have a similar make-up to whey protein.

The main goal of this research is to see if yeast protein can help you gain muscle in the same way that whey protein does. They will also be looking at whether yeast protein might offer other benefits, such as boosting your immune system or improving the helpful bacteria in your gut. By comparing these two proteins head-to-head, scientists hope to find out if yeast protein can be a great and sustainable alternative for people looking to improve their muscle health.

Taking part in this study would involve regular resistance training (like weightlifting) and taking a daily protein supplement for 16 weeks. The researchers are particularly interested in healthy adults between 18 and 35 years old who already have some experience with resistance training. This study could help us understand more about how different proteins support our bodies and contribute to our overall health and fitness.

Key takeaways

This study compares yeast protein to whey protein for muscle growth in healthy adults.
It's for people aged 18-35 who already do resistance training.
Participants take a daily protein supplement and continue exercising for 16 weeks.
The study aims to find a sustainable and effective protein source for muscle building.
You won't know which protein you're taking until the study ends (double-blind).

Who may be eligible?

This study is looking for healthy adults between 18 and 35 years old. To join, you need to already be doing some resistance training (like weightlifting) at least once a week for the last three months or more. You also need to be able to read and understand the study information and be willing to follow the study plan.

There are certain health conditions that would prevent you from taking part. For example, if you have conditions like diabetes, cancer, heart disease (including high blood pressure), or certain digestive issues like Crohn's disease or inflammatory bowel disease, you wouldn't be able to join. You also can't participate if you're pregnant, have allergies to ingredients in supplements, or are currently taking antibiotics.

Essentially, the study needs participants who are generally healthy and already somewhat active, to make sure the results clearly show the effects of the protein supplements and exercise without other health issues getting in the way.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

Are you between 18 and 35 years old?
Do you currently do resistance training (like weightlifting) at least once a week?
Do you consider yourself generally healthy, without serious ongoing health conditions?
Are you not pregnant and not taking antibiotics?
Do you have no known allergies to protein supplements?

Answer every question to see your result.

What does participation involve?

If you join this study, you would be randomly assigned to one of two groups: either the yeast protein group or the whey protein group. This means you won't get to choose which protein you receive. Both you and the study team measuring your progress won't know which protein you're taking until the study is over.

Your participation would last for 16 weeks. During this time, you would need to take 40 grams of your assigned protein supplement every day. You would also continue with your resistance training exercises. The study will involve regular check-ups and measurements to track your muscle mass and other health markers. The research will take place at the University of Alberta in Edmonton, Canada.

Potential risks and benefits

Participating in this study might offer some potential benefits, such as closely monitoring your muscle growth with expert guidance and potentially improving your fitness. You would also contribute to scientific knowledge about sustainable protein sources. Possible risks are generally low, mainly relating to potential mild digestive discomfort from the protein supplements or standard risks associated with regular exercise. There's always a chance that the protein supplement might not work as well for you as expected, or you could experience an allergic reaction if you have an unknown sensitivity. Remember, you can choose to leave the study at any time, for any reason, without it affecting your medical care.

Locations (1)

The University of Alberta North Campus
Verified postcode
Edmonton, Canada

Common questions

What is resistance training?

Resistance training involves exercises that make your muscles work against a weight or force, like lifting weights, using resistance bands, or doing bodyweight exercises like push-ups.

What is the difference between yeast protein and whey protein?

Whey protein comes from milk, often used in supplements. Yeast protein is made from yeast, offering a more sustainable, plant-based protein option that works similarly to whey.

Will I know which protein I am taking?

No, this is a 'double-blind' study. Neither you nor the people measuring your results will know if you're taking yeast protein or whey protein until the study is finished.

Will I have to pay to join the study?

No, clinical trials do not typically charge participants. The protein supplements and study-related assessments will be provided to you.

What if I experience side effects from the protein supplement?

You should report any unexpected effects to the study team immediately. They will advise you on what to do, and you have the right to withdraw from the study at any time.

How to find out more

Jianping Wu, PhD

jwu3@ualberta.ca (780) 492-6885 Official trial record

Always speak to your GP or specialist before deciding to take part in a study.