RecruitingNAINTERVENTIONAL

HIP Fracture Accelerated Surgical TreaTment And Care tracK 2 Trial

This research, called HIP ATTACK-2, is a study for people who have broken their hip and also have a specific type of heart issue (myocardial injury). It aims to find out if having surgery sooner for a hip fracture is better than waiting, particularly for reducing the risk of death in the first 90 days. The study will also look at other important things like how quickly people can walk again, how long they stay in the hospital, their pain levels, and their general quality of life. It compares quick medical checks and surgery to the standard way of doing things.

At a glance

Status

Recruiting

Phase

Sponsor

Population Health Research Institute

Enrolment target

1,100

Start

22 Nov 2021

Estimated completion

31 May 2027

Hip Fractures Myocardial Injury

What is this study about?

When someone breaks their hip, it's a serious injury, especially for older people. Sometimes, patients with a hip fracture also have a heart problem called a myocardial injury. This study, HIP ATTACK-2, is trying to figure out the best way to care for these patients. It specifically wants to see if getting surgery for the hip fracture very quickly, after a fast check-up by doctors, leads to better results than the usual approach where surgery might happen a bit later.

The main goal of the study is to see if having surgery sooner reduces the number of people who pass away within 90 days of their hip fracture. But the researchers will also be looking at many other important things. This includes how soon people can stand up and walk again, how long they need to stay in hospital, and if they experience other serious complications like further heart problems or strokes.

Ultimately, this research aims to improve care for people who have both a hip fracture and a heart issue. By comparing different approaches, the doctors hope to find out which method helps patients recover better, experience less pain, and have a better quality of life after such a serious injury.

Key takeaways

This study compares quick hip fracture surgery to standard care.
It's for people aged 45+ who have a hip fracture and a specific heart issue.
The main goal is to see if faster care reduces deaths and improves recovery.
Participation involves random assignment to a treatment group.
The study monitors health and recovery for 90 days.
You can withdraw from the study at any time.

Who may be eligible?

To join this study, you would generally need to be 45 years old or older and have broken your hip during normal daytime hours due to a minor fall or accident that requires surgery. A key requirement is that a blood test must show you have some heart muscle damage (called troponin elevation) at some point between your hip fracture and when the study begins.

There are also some reasons why you might not be able to join. For example, if you're taking certain blood-thinning medicines that can't be quickly reversed, or if the doctors feel surgery wouldn't be safe within six hours. You also wouldn't be able to participate if your hip fracture is unusual (like one near a previous hip replacement or an open wound), or if you need urgent surgery for a different life-threatening condition.

Additionally, if you have a very serious or unstable heart attack, or if you've already been part of this specific study before, you wouldn't be able to join. Of course, you must also be able to understand and agree to take part in the study.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

Are you 45 years old or older?
Did you break your hip during working hours from a minor fall?
Does a blood test show some stress or damage to your heart (troponin elevation)?
Do you need surgery for your hip fracture?
Are you able to agree to take part in the study?

Answer every question to see your result.

What does participation involve?

If you decide to take part in this study, you would be randomly assigned to one of two groups, like flipping a coin. One group would receive quicker medical checks and hip surgery, while the other would get the standard care. This is decided by chance, so neither you nor your doctors can choose which group you are in.

The study involves regular check-ups and assessments over a period of 90 days after your hip fracture. Doctors will monitor your recovery, including how well you can move, your pain levels, and your general health and quality of life. You'll likely have follow-up appointments and possibly questionnaires to complete during this time. The total duration of active follow-up for the study is 90 days.

Potential risks and benefits

Taking part in a study like this might offer a potential benefit of receiving closer monitoring or potentially earlier surgery, which could lead to better outcomes for your hip fracture and heart condition. However, there's also the chance that the accelerated treatment might not be better than standard care, or it could even have its own risks, though the study is designed to be as safe as possible. All medical procedures carry some risks, and by joining, you understand that your care pathway might be different from what you'd typically receive. Remember, you can choose to withdraw from the study at any time, for any reason, without it affecting your medical care.

Locations (70)

Chandler Regional Medical Center
Verified postcode
Chandler, United States· Recruiting
The Regents of the University of California
Verified postcode
Davis, United States· Recruiting
Yale New Haven Hospital
Verified postcode
New Haven, United States· Recruiting
Emory University at Grady Memorial Hospital
Verified postcode
Atlanta, United States· Recruiting
University of Maryland
Verified postcode
Baltimore, United States· Recruiting
Sinai Hospital of Baltimore
Verified postcode
Baltimore, United States· Recruiting
Tufts Medical Center
Verified postcode
Boston, United States· Recruiting
Lahey Hospital and Medical Center
Verified postcode
Burlington, United States· Recruiting
University of Michigan
Verified postcode
Ann Arbor, United States· Recruiting
Mayo Clinic
Verified postcode
Rochester, United States· Recruiting
Bryan Medical Center
Verified postcode
Lincoln, United States· Recruiting
University Medical Center of Southern Nevada
Verified postcode
Las Vegas, United States· Recruiting

Common questions

What is 'myocardial injury'?

Myocardial injury means there's been some stress or damage to your heart muscle, often shown by a simple blood test called troponin, which can be raised after a hip fracture.

Why is 'accelerated surgery' being looked at?

Doctors want to see if operating on a broken hip very quickly, especially in patients with heart issues, can help them recover better and reduce serious complications.

Will I get to choose if I have faster surgery?

No, if you join the study, you'll be randomly assigned to either the faster surgery group or the standard care group. This is like drawing lots to make it fair.

How long will the study follow me?

The study will follow your progress and outcomes for about 90 days (about three months) after your hip fracture and when you start the study.

What if I change my mind about participating?

You are free to leave the study at any time, for any reason. Doing so will not affect the medical care you receive for your hip fracture.

How to find out more

Valerie Harvey

valerie.harvey@phri.ca 905-297-3479 Official trial record

Always speak to your GP or specialist before deciding to take part in a study.