AuthorisedTherapeutic exploratory (Phase II)Interventional

REpurposed drug evaluation for DEceleration of immunE aging & Mitigation of chronic inflammation (REDEEM)

Doctors are running a study called REDEEM to explore if a medicine that's already used for other conditions could help with two important health issues: 'immune aging' and 'chronic inflammation'. Immune aging means your body's defence system isn't as strong as it used to be, making you more prone to illness. Chronicinflammation is when your body has long-lasting swelling and irritation, which can lead to various health problems. This study is in an early stage (Phase 2), meaning researchers are still learning about the treatment. They want to see if this existing medicine can safely slow down the aging of your immune system and reduce long-term inflammation, potentially improving your overall health. It's open to adults aged 18 and over, of any gender.

At a glance

Status

Authorised

Phase

Therapeutic exploratory (Phase II)

Sponsor

Radboud universitair medisch centrum Stichting

Enrolment target

150

Start

08 Jun 2026

Immune Aging, Chronic inflammation

What is this study about?

You know how our bodies change as we get older? Well, our immune system – that's our body's amazing defence against bugs and illnesses – also changes. Sometimes, it doesn't work as well as it used to, which doctors call 'immune aging'. This can make us more likely to get sick or take longer to recover. At the same time, many people experience 'chronic inflammation', which is like a low-level, long-lasting irritation or swelling inside the body. This isn't the same as stubbing your toe; it's something that can happen quietly and contribute to various health issues over time.

This study, called REDEEM, is like a detective mission. Researchers are looking at a medicine that's already approved and used for other things, to see if it could have a new and important job: helping with immune aging and chronic inflammation. They want to find out if this medicine can make our immune systems work better as we age and reduce that long-term inflammation.

This is an early-stage study, sometimes called a Phase 2 trial. This means the doctors are carefully exploring if the treatment is safe for this new purpose and if it shows promising signs of helping. They're not just giving a new medicine; they're trying to repurpose something that already exists, hoping to find a new way to keep people healthier as they get older.

Key takeaways

The study explores if an existing medicine can improve immune health and reduce inflammation.
It's open to adults aged 18 and older, of any gender.
Participation involves taking the study medicine and attending regular check-up visits.
Researchers are carefully testing for safety and how well the treatment works.
You can withdraw from the study at any point without affecting your healthcare.

Who may be eligible?

To join this study, you need to be an adult, meaning you must be 18 years old or older. There is no upper age limit, so people of all adult ages can be considered. Both men and women are welcome to take part.

Before you can join, the study team will ask you some questions about your health and do some checks. These checks are important to make sure the study is safe for you and that you meet all the specific requirements for this particular research. For example, they might need to make sure you don't have certain other health conditions or are not taking medicines that could interfere with the study drug.

It's important to remember that not everyone who is interested will be able to join. The study team has strict rules about who can take part to make sure the results are clear and that everyone is safe. They will explain everything clearly if you are interested.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

Are you 18 years old or older?
Are you able to attend regular appointments at the study clinic?
Are you willing to take a study medicine as instructed?
Are you willing to have blood tests?
Do you understand that you might need to meet other specific health criteria?

Answer every question to see your result.

What does participation involve?

If you decide to take part in the REDEEM study, you would first have an initial visit where the study team will explain everything in detail and check if you meet all the requirements. This might include a general health check-up, some blood tests, and answering questions about your health history.

If you are eligible, you would likely receive the study medicine, probably in tablet form, which you would take regularly as instructed. You would also have several follow-up visits to the clinic over a period of time. During these visits, doctors would monitor your health closely, including more blood tests and possibly other assessments, to see how the medicine is affecting your immune system and inflammation. They will check for any side effects and how you are feeling generally.

The total amount of time you would be involved in the study would depend on the specific plan, which the study team will go through with you in detail. This could range from several months to a year or more. Throughout the study, you would also have a dedicated team to answer any questions and support you.

Potential risks and benefits

Taking part in any study has potential benefits and risks. A potential benefit of this study is that the medicine might help to improve your immune system function and reduce chronic inflammation, which could lead to better health. However, there's no guarantee the medicine will work for you, or that it will be better than existing treatments. As with any medicine, there is a possibility of side effects, which could be mild or, in rare cases, more serious. The study team will explain all known side effects. You are free to withdraw from the study at any time, for any reason, without it affecting your medical care.

Locations (1)

Some site locations are approximate. We're improving this — please verify with the trial team before travelling.

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Unverified
Netherlands

Common questions

What is 'immune aging'?

It's when your body's defence system, your immune system, doesn't work as strongly as it used to as you get older, making you more prone to illness.

What does 'chronic inflammation' mean?

It's a long-lasting, low-level irritation or swelling inside your body that can contribute to health problems over time.

Is this a brand new medicine?

No, it's a medicine that's already approved and used for other conditions, but researchers are seeing if it can help with immune aging and inflammation.

How long would I be in the study?

The exact duration varies, but the study team will explain the full timeline, which could be several months or more, during your initial visit.

Can I stop taking part if I change my mind?

Yes, you can leave the study at any time, for any reason, and it won't affect your regular medical care.