Evaluation of the Reproducibility of the Automated Measurement of the Extent of ILD on Chest CT
This study aims to evaluate how consistently automated tools measure lung damage in patients with Interstitial Lung Disease (ILD) using CT scans. Currently, the amount of lung damage seen on a CT scan is a key indicator of how the disease might progress. New automated computer programs can quickly measure this damage, but we need to know how reliable these measurements are. We will repeat CT scans on the same day and use different computer programs to analyse them. This will help us understand if the same results are consistently produced, even with slight differences in how the scan is taken or which software is used. Our goal is to ensure automated measurements are accurate and trustworthy for people with ILD.
At a glance
What is this study about?
If you have Interstitial Lung Disease (ILD), your doctor often uses CT scans to look at your lungs and understand how much of your lung tissue is affected. This information is very important because it helps them predict how your disease might change over time and plan your care.
In recent years, computer programs have been developed that can automatically measure the amount of ILD on a CT scan. These tools are designed to be quick and precise. The idea behind these automated measurements is that they should give consistent results every time. However, even small things can change how a CT scan looks, like how deeply you breathe in or the specific settings used when the scan is processed. Because of this, we need to check how reliable these automated measurements truly are when the whole process, from scanning to measurement, is considered.
This study will help us understand how much the automated measurements of ILD can vary. We will do this by giving patients two CT scans on the same day and then using different computer programs to measure the lung damage on both scans. By comparing these results, we can learn about the consistency of these measurements and how factors like the type of ILD might affect them. Ultimately, this research will help us ensure that automated CT scan measurements are as accurate and dependable as possible for people living with ILD.
Key takeaways
- The study checks how reliable computer tools are for measuring lung damage from ILD on CT scans.
- It involves getting two CT scans on the same day.
- This helps improve accuracy for future ILD diagnoses and follow-ups.
- There are no study medications or extra visits beyond the scan day.
- Participation will help doctors better understand ILD progression.
Who may be eligible?
To join this study, participants must be at least 18 years old and have a confirmed diagnosis of Interstitial Lung Disease (ILD), specifically either Idiopathic Pulmonary Fibrosis or ILD linked to a connective tissue disease. You also need to be a patient at one of the hospitals taking part in the study and be scheduled to have a chest CT scan as part of your regular check-up. You must also be covered by the French national social security system and agree to take part by signing a consent form.
There are certain reasons why someone might not be able to join. These include if you are currently experiencing a sudden worsening of your ILD, if you are pregnant, or if you can't hold your breath for 10 seconds during the CT scan. You also can't participate if you're in the waiting period after another research study, or if your doctor needs special extra CT images taken in certain positions.
Could this study suit you?
Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.
- Are you 18 years old or older?
- Do you have a diagnosis of Idiopathic Pulmonary Fibrosis or connective tissue disease-related ILD?
- Are you a patient at one of the hospitals participating in this study?
- Are you able to hold your breath for 10 seconds?
- Are you scheduled for a chest CT scan soon as part of your regular care?
- Are you currently pregnant or having a sudden worsening of your ILD?
What does participation involve?
If you decide to take part in this study, you will have two chest CT scans on the same day. These scans will be done as part of your usual medical care, but one will be an additional scan for the study. There are no study medications involved. We won't need any extra follow-up visits specifically for this study beyond your regular appointments. The total duration of your active participation will be limited to that single day when the two CT scans are performed.
Potential risks and benefits
Locations (6)
- APHP - Bichat hospital - RadiologyVerified postcodeParis, France· Recruiting
- APHP - Bichat hospital - RheumatologyVerified postcodeParis, France· Recruiting
- APHP - Cochin Hospital - Internal medicineVerified postcodeParis, France· Recruiting
- APHP - Cochin Hospital - PneumologyVerified postcodeParis, France· Recruiting
- APHP - Cochin Hospital - RadiologyVerified postcodeParis, France· Recruiting
- APHP - Bichat Hospital - PneumologyVerified postcodeParis, France· Recruiting
Common questions
What is an Interstitial Lung Disease (ILD)?
ILD is a group of conditions that cause scarring and stiffness in the lungs, making it harder to breathe.
What is a CT scan?
A CT scan uses X-rays and computer processing to create detailed images of your chest and lungs.
Will I have more radiation exposure?
Yes, you will have one extra CT scan, meaning a small additional amount of radiation exposure, but it's generally considered safe by doctors for research purposes.
Will this study change my treatment?
No, this study is about checking how accurate certain measurements are; it won't change your current medical treatment.
Who is funding this research?
The information provided doesn't specify the funding source for this study.
How to find out more
Guillaume CHASSAGNON, MD, PhD
Always speak to your GP or specialist before deciding to take part in a study.
Interested in taking part?
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