Optimization of the Management of Non-Traumatic Intracerebral Hemorrhage (OPT-ICH)
This study, called OPT-ICH, is looking at how to best treat a type of stroke known as an intracerebral haemorrhage (ICH). This is when bleeding occurs inside the brain, and it's a very serious condition. Doctors at the University Hospital of Tours in France want to understand how care is currently given and if a detailed, step-by-step treatment plan can help patients live longer and reduce long-term problems or disabilities. The study will involve looking at patient information from the past and observing patients in the future who receive this new, organised approach to care.
At a glance
What is this study about?
This study, called OPT-ICH, is all about improving how we look after people who have a specific type of stroke. This stroke is called an 'intracerebral haemorrhage' (ICH), which means there's bleeding inside the brain. It's a very serious condition, accounting for a significant number of all strokes. Sadly, many people don't survive, and those who do often face long-term health challenges or disabilities, such as problems with movement, memory, or even developing conditions like epilepsy or dementia.
Good news is, doctors believe that if patients get the right care really quickly from expert staff in specialised units, their chances of recovery can improve. This study aims to check how patients with ICH are currently being cared for at a French hospital and then see if a new, structured approach to their treatment, introduced early on, can make a real difference. They want to find out if this improved care can lead to fewer deaths and less disability, both in the short term and over several years.
To do this, the study has two main parts. First, they will look back at the records of patients treated between 2018 and 2021 to see how things were done previously. Second, they will observe new patients who come into the hospital with an ICH. These new patients will receive care following a detailed plan. This plan includes things like getting urgent brain scans, being admitted to a special unit, receiving quick medication to control blood pressure or reverse blood thinners, and having regular check-ups and follow-up scans over several months and years to see how they are recovering.
Key takeaways
- Focuses on improving care for a serious type of stroke (ICH).
- Aims to reduce deaths and long-term disability.
- Compares current care to a new, structured treatment plan.
- Involves detailed medical assessments and long-term follow-up.
- Study is observational; no new drugs are given.
Who may be eligible?
To be considered for this study, you would need to be aged 18 or over. You must also have been admitted to the emergency department of a university hospital (specifically Tours, Angers, or Poitiers in France) and have had an intracerebral haemorrhage (ICH) confirmed by a brain scan, like a CT scan or MRI, when you arrived at the hospital.
There's only one main reason you wouldn't be able to be part of the study: if you had specifically said that you didn't want your health information to be collected for research purposes.
Could this study suit you?
Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.
- Are you 18 years old or older?
- Were you admitted to specific university hospitals (Tours, Angers, Poitiers in France) due to an emergency?
- Was your condition confirmed as an intracerebral haemorrhage (ICH) by a CT or MRI scan when you arrived at the hospital?
- Have you not previously stated that you don't want your health information used for research?
What does participation involve?
If you were to take part in this study, it's important to understand that you wouldn't be given any experimental new drugs. Instead, the study focuses on how care is delivered. The main thing is that your care would follow a specially designed plan for patients with intracerebral haemorrhage (ICH). This plan includes several steps right from when you arrive at the hospital.
These steps involve getting urgent brain scans (like an MRI or CT scan), being admitted to a specialist unit, and receiving quick medication if needed, for example, to lower blood pressure or reverse blood thinners. Doctors would also consult with brain surgeons soon after your arrival.
Over time, you would have follow-up brain scans after 1-2 days and again after 3-6 months. Your doctors would also check on your recovery and brain function at 6 months and 2 years after your stroke. For some, a more detailed assessment of mental abilities might be included at these times.
Potential risks and benefits
Locations (3)
- University Hospital of AngersVerified postcodeAngers, France· Recruiting
- University Hospital of PoitiersVerified postcodePoitiers, France· Recruiting
- University Hospital Center of ToursVerified postcodeTours, France· Recruiting
Common questions
What is an intracerebral haemorrhage (ICH)?
It's a type of stroke caused by bleeding inside the brain, which can be very serious.
Is this study testing a new medication?
No, this study is looking at how to organise patient care better, not new drugs.
Will I have extra tests if I join?
You'll have special brain scans and assessments as part of the detailed care plan, but these are for your treatment and follow-up.
How long will I be followed in the study?
Doctors will check on your progress and recovery for up to two years after your stroke.
What if I change my mind about being in the study?
You can withdraw your permission for your data to be used at any time, and it won't affect your medical care.
How to find out more
Marco PASI, MD, PHD
Always speak to your GP or specialist before deciding to take part in a study.
Interested in taking part?
Discussion
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