Intent of Surgery for IPMN
This study is reviewing past surgeries for a pancreatic condition called Intraductal Papillary Mucinous Neoplasm (IPMN). Researchers are looking at patient records from 2015 to 2025 to understand why surgery was performed in each case. They want to see how many cancers found within IPMN were unexpected discoveries after surgery. The study also compares patients whose IPMN-related cancers were found during regular check-ups versus those found by chance. Ultimately, the goal is to improve how doctors predict which IPMN cases are more likely to become malignant (cancerous), helping them make better decisions about treatment for future patients.
At a glance
What is this study about?
This research is looking at a condition called Intraductal Papillary Mucinous Neoplasm, or IPMN for short. IPMN is a type of growth that can appear in the pancreas, an organ that helps with digestion and making hormones. While many IPMNs are harmless, some can become cancerous over time. Doctors often recommend surgery for IPMN, but deciding who needs surgery and when can be complex.
This study is a bit like looking through old patient files. Doctors are reviewing records of people in a multi-centre study (meaning it involves several hospitals) who had surgery for IPMN between 2015 and 2025. They want to understand the main reasons why surgery was chosen for each patient. They also want to see how often a cancer related to IPMN was only discovered after surgery, rather than expected beforehand. This helps them understand whether some cancers are being missed or found late.
The researchers will also compare different groups of patients. For example, they'll look at those whose IPMN-related cancer was found during routine check-ups versus those where the cancer was found by chance, perhaps during tests for another problem. By doing this, they hope to get a clearer picture of the warning signs that an IPMN might become serious. Ultimately, the aim is to find better ways to predict which IPMNs are likely to turn cancerous, helping doctors make more accurate decisions for patients in the future about whether surgery is needed.
Key takeaways
- This study reviews past patient records of IPMN surgery.
- It aims to understand why surgery was performed and how effectively cancer was detected.
- The goal is to improve predictions for which IPMNs might become cancerous.
- It helps doctors make better treatment decisions for future patients.
- Your direct involvement is not required as it uses existing data.
Who may be eligible?
This study is looking at medical records of people who have already had surgery for a condition called IPMN. To be included, you must have been 18 years old or older at the time of your surgery.
Your surgery must have taken place between 1st July 2015 and 1st July 2025. This includes cases where the IPMN was considered low risk, high risk, or had already become cancerous.
You would not be included in this study if you also had another specific type of pancreatic cancer called concomitant pancreatic ductal adenocarcinoma at the same time as your IPMN.
Could this study suit you?
Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.
- Were you 18 years old or older when you had your surgery for IPMN?
- Did you have surgery for IPMN? (This includes low-risk, high-risk, or cancerous IPMN.)
- Did your IPMN surgery happen between 1st July 2015 and 1st July 2025?
- Did you NOT also have a different type of pancreatic cancer (called PDAC) at the same time as your IPMN?
What does participation involve?
This study is reviewing existing medical records, so you would not need to do anything or attend any extra appointments. There are no new tests, medicines, or follow-up visits involved for patients, as the information is gathered from historical data. Your medical information from your surgery for IPMN would be included as part of the study analysis, if it meets the criteria. This type of study does not involve direct participation from patients once the data has been collected during their treatment.
Potential risks and benefits
Locations (14)
- Mayo ClinicVerified postcodePhoenix, United States· Recruiting
- Johns Hopkins UniversityVerified postcodeBaltimore, United States· Recruiting
- Massachusetts General HospitalVerified postcodeBoston, United States· Recruiting
- Mayo ClinicVerified postcodeRochester, United States· Recruiting
- NYU Langone HealthVerified postcodeNew York, United States· Recruiting
- Memorial Sloan KetteringVerified postcodeNew York, United States· Recruiting
- Duke UniversityVerified postcodeDurham, United States· Recruiting
- MD Anderson Cancer CenterVerified postcodeHouston, United States· Recruiting
- Nanjing UniversityVerified postcodeNanjing, China· Recruiting
- Heidelberg UniversityVerified postcodeHeidelberg, Germany· Recruiting
- San Raffaele HospitalVerified postcodeMilan, Italy· Recruiting
- Padua UniversityVerified postcodePadua, Italy· Recruiting
Common questions
What is IPMN?
IPMN (Intraductal Papillary Mucinous Neoplasm) is a type of growth in the pancreas, an organ that helps digest food and make hormones. While some are harmless, others can become cancerous.
Will I have to do anything if my records are included?
No, you don't need to do anything. This study is reviewing past medical records, so there are no extra appointments, tests, or treatments for you.
Will my name be shared?
No, your personal information will be kept private. Researchers will look at your medical data but will not share your name or identifying details.
Who is eligible for this study?
This study includes records of people aged 18 or over who had surgery for IPMN between July 2015 and July 2025. It excludes those with a specific other type of pancreatic cancer at the same time.
How will this study help?
The study aims to help doctors better understand IPMN and improve their ability to predict which cases might become serious, leading to better treatment decisions for future patients.
How to find out more
Camila Hidalgo Salinas, MD
Always speak to your GP or specialist before deciding to take part in a study.
Interested in taking part?
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