RecruitingOBSERVATIONAL

ECMM Candida Registry - CandiReg

The CandiReg study is gathering information globally about a serious fungal infection called invasive candidiasis, caused by Candida yeast. This condition can affect different parts of the body. The study wants to learn more about how common it is, whether rates are changing, and which people are most at risk of getting it. Researchers will also look at how effective current treatments are and if the yeast is becoming resistant to medicines. By understanding these things better, the study hopes to improve how doctors diagnose and treat invasive candidiasis in the future, ultimately leading to better health outcomes for patients. It's collecting data from medical records, not testing new drugs.

At a glance

Status

Recruiting

Sponsor

University of Cologne

Enrolment target

2,000

Start

18 Jan 2018

Estimated completion

31 Dec 2026

Invasive Candidiases

What is this study about?

This study, known as CandiReg, is being run by a group of experts called the European Confederation of Medical Mycology (ECMM). Its main goal is to collect detailed information from hospitals all over the world about a serious type of yeast infection called invasive candidiasis. Imagine it like a big, global effort to understand this infection much better.

Currently, we don't know enough about how common invasive candidiasis is, how it affects patients over time, or the specific types of Candida yeast that cause it. The CandiReg study aims to fill these gaps in our knowledge. By gathering this data, researchers hope to see if the number of cases is going up or down, identify groups of people who are more likely to get the infection, and understand how the yeast might be becoming resistant to medicines.

The information collected will be crucial for developing better ways to spot the infection early, decide on the best treatments, and make sure those treatments are working well. Ultimately, this study isn't about testing a new drug; it's about building a strong foundation of knowledge that can help doctors and healthcare systems improve care and save lives when dealing with invasive candidiasis.

Key takeaways

CandiReg is an international study collecting medical information.
It focuses on serious Candida yeast infections, called invasive candidiasis.
The study aims to improve understanding of causes, treatments, and outcomes.
Your medical record data could help improve care for future patients.
No new treatments or hospital visits are involved for you.
All your personal information will be kept private and anonymised.

Who may be eligible?

To be included in this study, you would need to have a confirmed diagnosis of an invasive Candida infection. This means tests like those on blood, tissue samples, or special scans have shown that Candida yeast is causing a serious infection inside your body. A specific type called hepatosplenic candidiasis, which affects the liver and spleen but might not show up on all tests, also qualifies if there are clear signs of a widespread infection.

They are also looking for 'control' patients, which are people without this specific infection but who are similar in age, other health conditions, and how long they've been in hospital. This helps researchers compare people with and without the infection to understand it better.

You would not be able to join if your Candida infection is only on the surface of your skin, in your urine without spreading, or found in your gut without causing a widespread problem. This study is specifically for the more serious, invasive type of infection.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

Do I have a confirmed deep or widespread Candida infection?
Has a doctor told me I have 'invasive candidiasis'?
Is my infection more serious than just skin thrush or a bladder infection?
Am I open to having information from my medical records used for research?

Answer every question to see your result.

What does participation involve?

If you are eligible, your participation would involve the collection of information from your medical records by the research team. This study is observational, meaning researchers will look at data about your diagnosis, the types of tests you had, the treatments you received (both initial and any changes), and how you recovered. You would not receive any new or experimental treatments as part of this study, nor would there be any additional hospital visits specifically for the study. The total duration of your participation would be based on the information available in your medical records regarding your infection and recovery.

Potential risks and benefits

There are no direct medical benefits or risks to you for participating in this study, as it only involves collecting information from your existing medical records. You would not undergo any extra procedures or receive any new medication. The main benefit is that the information gathered will help doctors and researchers worldwide better understand invasive Candida infections, potentially leading to improved diagnosis, treatments, and patient care for others in the future. You always have the right to withdraw your consent for your de-identified medical data to be used in the study at any time without affecting your medical treatment.

Locations (1)

University Hospital Cologne
Verified postcode
Cologne, Germany· Recruiting

Common questions

What is 'invasive candidiasis'?

It's a serious infection caused by a type of yeast called Candida, which spreads inside the body, unlike common thrush which is usually on the surface.

Will I receive any new treatments if I join this study?

No, this study is about collecting information from your existing medical records; you won't receive any new or experimental treatments.

Is my personal information kept private?

Yes, any information from your medical records will be handled with strict confidentiality and usually made anonymous so it can't be traced back to you.

How long does participation last?

Your participation involves researchers reviewing your medical records related to your infection, so there's no set time you're 'in' the study personally as a participant.

Why is this study important?

It helps doctors worldwide better understand serious Candida infections, which can lead to improved ways of diagnosing and treating people in the future.

How to find out more

Oliver Cornely, MD

oliver.cornely@uk-koeln.de +49 221 478 Official trial record

Always speak to your GP or specialist before deciding to take part in a study.