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The K-Map Study, Global Prevalence of KC

The K-Map Study is trying to find out how many children and young adults around the world have an eye condition called keratoconus. This condition can affect eyesight, often in both eyes. The study uses a special camera, called a Pentacam, to take pictures of the front of the eye. They are looking at young people aged 6 to 23 who are visiting the doctor for reasons other than an eye problem. By checking healthy-looking eyes from different countries, researchers hope to get a clearer picture of how common keratoconus really is. They believe it might be more widespread than current figures suggest, and this research could help us understand it better.

At a glance

Status
Recruiting
Sponsor
University Hospital, Geneva
Enrolment target
20,000
Start
28 Dec 2015
Estimated completion
01 Feb 2030

What is this study about?

The K-Map Study is investigating an eye condition called keratoconus. This condition affects the clear front part of your eye, called the cornea, making it gradually thin and bulge forward into a cone shape. This change can make your vision blurry or distorted, and it often affects both eyes, though sometimes one eye is more affected than the other. It usually starts when people are young.

At the moment, we don't have a full picture of how many young people have keratoconus globally, especially because it can be subtle in its early stages. This study aims to use modern eye scanning equipment, specifically a rotating Scheimpflug camera (like the Pentacam HR), to get a better understanding. This special camera can take detailed pictures of the cornea and detect very early changes that might not be obvious during a regular eye check-up.

The main goal is to see if keratoconus is actually more common in children and teenagers than we currently believe. Doctors often rely on old information, and with new technology, we might find that more people have this condition. By gathering information from different countries across the world, researchers hope to update our understanding of keratoconus and help doctors identify it earlier, which could lead to better ways of managing it in the future.

Key takeaways

  • The K-Map Study is researching an eye condition called keratoconus.
  • It aims to find out how common keratoconus is in young people (6-23 years old) globally.
  • Participation involves a quick, painless eye scan (Pentacam) on both eyes.
  • You don't need to have eye symptoms or a known eye problem to join.
  • The research helps scientists better understand keratoconus for future patient care.
  • You can withdraw from the study at any time.

Who may be eligible?

The K-Map Study is looking for children and young adults from ages 6 to 23 years old. This study is open to both boys and girls.

You might be able to join if you are coming in for a doctor's appointment that isn't for your eyes. This means they are looking at people who might not even know they have an eye issue. Your parent or legal guardian will need to sign a consent form, agreeing for you to take part, and you should be happy to follow the study's instructions for its duration.

You won't be able to join if you already have an eye condition or if you are pregnant or breastfeeding. The study wants to look at eyes that appear healthy to the person, so if you have a known eye problem, it wouldn't be suitable for this research.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

  1. Am I between 6 and 23 years old?
  2. Am I attending a doctor's appointment for a reason other than an eye problem?
  3. Do I (or my parents/guardians) agree to sign a consent form?
  4. Do I not currently have any other eye conditions?
  5. Am I not pregnant or breastfeeding (if applicable)?
Answer every question to see your result.

What does participation involve?

If you decide to take part in the K-Map Study, it's quite straightforward. You will have a special eye scan using a machine called a Pentacam. This machine takes pictures of the front of your eye, and it will be done on both eyes. This process is quick and doesn't involve any drops or pain. You won't need to take any medication or have follow-up visits specifically for this study. The entire appointment should be relatively short, often done while you are already at a clinic for another reason (not eye-related).

Potential risks and benefits

Taking part in this study could help doctors understand keratoconus better, potentially leading to earlier detection and improved care for others in the future. The eye scan itself is very safe and painless, with no known risks from the Pentacam machine. There are no direct personal health benefits for you from participating, as the study is purely for research. You are free to change your mind and withdraw from the study at any time, for any reason, without it affecting your medical care.

Locations (12)

  • USC Roski Eye Institute
    Verified postcode
    Los Angeles, United States· Recruiting
  • Eye Hospital of Wenzhou Medical College
    Verified postcode
    Wenzhou, China· Recruiting
  • Verified postcode
    Zagreb, Croatia· Recruiting
  • Verified postcode
    Alexandria, Egypt· Recruiting
  • Verified postcode
    Homburg, Germany· Recruiting
  • Verified postcode
    Isfahan, Iran· Recruiting
  • Verified postcode
    Amman, Jordan· Recruiting
  • Verified postcode
    Monterrey, Mexico· Recruiting
  • Verified postcode
    Lima, Peru· Recruiting
  • Ufa Eye Research Intitute
    Verified postcode
    Ufa, Russia· Completed
  • King Saud University
    Verified postcode
    Riyadh, Saudi Arabia· Completed
  • Verified postcode
    Bukhara, Uzbekistan· Recruiting

Common questions

What is keratoconus?

It's an eye condition where the clear front part of your eye (the cornea) thins and bulges forward, which can make your vision blurry.

Will I get eye drops during the scan?

No, the special camera scan for this study is quick and doesn't usually require any eye drops.

What if they find something with my eyes?

The study's goal is research. If they find something unexpected, they will follow their procedures for letting you know and advising on next steps.

How long will it take if I participate?

The eye scan itself is very quick, usually done during another non-eye-related doctor's visit, so it won't add much time to your appointment.

Do I have to do anything else after the scan?

No, there are no medications to take or follow-up visits required specifically for this research study.

How to find out more

Farhad Hafezi, MDPhD

Always speak to your GP or specialist before deciding to take part in a study.

Interested in taking part?

Register your interest

Share your details and the research team for "The K-Map Study, Global Prevalence of KC…" will contact you if you may be eligible. Always speak to your GP before agreeing to take part.

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