RecruitingOBSERVATIONAL

Intelligent Lung Support in the Intensive Care Unit

This study is about a smart computer program called IntelliLung, which uses artificial intelligence (AI) to help doctors and nurses in intensive care units. This program gives advice on how to set up breathing machines (ventilators) for patients who need help breathing. The researchers are observing patients who are already using these breathing machines, including those with severe lung problems. They want to find out how well the breathing machine settings chosen by the healthcare staff match the recommendations from the IntelliLung program. The main goal is to improve how breathing machines are used so that patients get the best possible support.

At a glance

Status

Recruiting

Sponsor

Technische Universität Dresden

Enrolment target

530

Start

25 May 2025

Estimated completion

01 Dec 2027

Mechanical Ventilation Intensive Care Medicine

What is this study about?

This study is looking at a new computer system called IntelliLung. This system uses artificial intelligence, which means it's a smart computer program designed to help doctors and nurses. Its main job is to give advice on how to set up breathing machines, also known as ventilators, for patients who are very sick in the intensive care unit (ICU).

When someone is very ill and can't breathe well on their own, a breathing machine can help them by pushing air into their lungs. Setting up these machines correctly is very important to make sure the patient gets the right amount of air and support. The IntelliLung system provides suggestions to healthcare staff to help them make these decisions.

In this study, researchers are watching how doctors and nurses set up these breathing machines for patients. They are comparing these real-life settings to the advice given by the IntelliLung system. This helps them understand how useful the system is and if it can help improve how patients are cared for when they need help breathing.

Key takeaways

This study uses a computer program (IntelliLung) to advise on breathing machine settings.
It aims to see how common doctor choices compare to the program's advice.
This is an observation study, so actual medical care won't change.
The goal is to improve breathing machine use for future patients.
Participation will not involve new treatments or medicines.

Who may be eligible?

To be part of this study, you would need to be at least 18 years old. You would also need to be in the intensive care unit and connected to a breathing machine, with the expectation that you'll need this help for more than 24 hours.

There are also some reasons why you wouldn't be able to join. For example, if it's expected that you might pass away within the next two days, or if you're already involved in another study testing a breathing machine, you wouldn't be able to participate here. Also, if you're part of the team running the study or are in prison, you wouldn't be included.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

Are you 18 years old or older?
Are you currently in intensive care and using a breathing machine?
Are you expected to need the breathing machine for more than 24 hours?
Are you not currently part of another study testing a breathing machine?
Are you able to give your permission (or have someone legally do so for you)?

Answer every question to see your result.

What does participation involve?

If you are eligible, taking part in this study would involve standard monitoring as you would already be receiving in the intensive care unit while on a breathing machine. The study is observational, meaning the researchers will be collecting information about how your breathing machine is set up and comparing it to the IntelliLung system's advice. You would not be given any new medication or special treatments just for the study. The doctors and nurses will continue to provide your care as usual. There are no extra visits or assessments beyond your normal hospital care. The total duration of your participation would depend on how long you need mechanical ventilation.

Potential risks and benefits

Since this is an observational study and the IntelliLung system is there to support your existing care, there are unlikely to be new risks for you. Your medical team will continue to make all decisions about your treatment. The potential benefit is that by understanding how systems like IntelliLung can help, future patients might receive even better care on breathing machines. You have the right to withdraw your consent at any time, which means you can stop being part of the study information gathering without it affecting your medical care.

Locations (5)

Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany
Verified postcode
Dresden, Germany· Recruiting
Dipartimento di Scienze Chirurgiche e Diagnostiche Integrate, University of Genoa, Genoa, Italy
Verified postcode
Genova, Italy· Not yet recruiting
Department of Anaesthesiology and Intensive Care, National Medical Institute of the Ministry of Interior and Administration, Warsaw, Poland
Verified postcode
Warsaw, Poland· Recruiting
Department of Intensive Care Medicine. Hospital Universitario de La Princesa. Universidad Autonoma de Madrid, Madrid, Spain
Verified postcode
Madrid, Spain· Not yet recruiting
Critical Care Department, Parc Taulí Hospital Universitari, Institut d'Investigació I Innovació Parc Taulí (I3PT-CERCA), Sabadell, Spain
Verified postcode
Sabadell, Spain· Recruiting

Common questions

What is IntelliLung?

IntelliLung is a smart computer program that uses artificial intelligence to help doctors and nurses decide the best settings for breathing machines.

Will the computer program make my medical decisions?

No, the IntelliLung program only gives recommendations. Your doctors and nurses will always make the final decisions about your care and how your breathing machine is set up.

Is this study giving me new medicine or treatment?

No, this study is just observing. You will continue to receive the same medical care you would otherwise get, including your breathing machine settings.

Who can take part in this study?

Adults (18 or older) in the intensive care unit who are using a breathing machine and are expected to need it for more than a day.

What if I change my mind about being in the study?

You can decide to stop being part of the study at any time, and it will not affect the medical care you receive in any way.

How to find out more

Jakob Wittenstein, M.D.

jakob.wittenstein@ukdd.de +49 351 458 19777 Official trial record

Always speak to your GP or specialist before deciding to take part in a study.