Reproducibility of Multiparametric Renal Magnetic Resonance Imaging on 1.5T MRI Scanners
This research aims to check how reliable and consistent a special kidney scan, called multiparametric renal MRI, is when performed on the widely available 1.5T MRI machines. We want to see if the scan results are similar when repeated and if they give consistent information across different hospitals. We will also investigate if age or sex affects these results. Ultimately, this study will help us understand if these advanced kidney scans can be used more widely to better diagnose, monitor, and treat kidney conditions in the future. We're also comparing these findings with scans from stronger 3T MRI machines to see how they differ.
At a glance
What is this study about?
Imagine your doctor wants to get a really detailed picture of your kidneys using a special kind of MRI scan. This advanced scan, called multiparametric renal MRI, promises to tell us a lot more about how your kidneys are working than standard tests. It's a non-invasive way to understand your kidney health better, potentially helping with early diagnosis, predicting how a condition might progress, and guiding treatment.
However, before these amazing scans can be used regularly in hospitals for everyone, we need to make sure they give consistent and reliable results. Right now, different hospitals might do these scans slightly differently, making it hard to compare results. This study is a crucial step towards making sure these scans are done in a standard way across all centres, so doctors can trust the information they get.
While some advanced hospitals have very powerful 3T MRI scanners, most places use the more common 1.5T MRI scanners. This study specifically focuses on these 1.5T machines to see how consistently they perform these special kidney scans. We also want to understand if factors like your age or whether you are male or female affect the scan's consistency. For some participants, we'll even compare results from 1.5T scans with those from 3T scans to see if the machine strength makes a difference. This information will help bring these valuable kidney scans closer to being a routine part of kidney care for everyone.
Key takeaways
- The study checks how reliable a special kidney MRI scan is.
- It focuses on common 1.5T MRI machines.
- We need consistency for these scans to be used in hospitals.
- Healthy volunteers aged 18-70 are needed.
- Your participation helps improve kidney diagnosis for future patients.
Who may be eligible?
To join this study, we're looking for healthy volunteers between the ages of 18 and 70. You must have normal kidney function and normal blood pressure without needing medication for it. We'll check your urine to make sure there's no blood or protein, as these could suggest a kidney problem.
There are some reasons why you wouldn't be able to take part. For example, if you've already been in this specific study, have a fear of enclosed spaces (claustrophobia), are pregnant, or have certain metal implants like a pacemaker that aren't safe for an MRI scan. We also can't include you if you're currently taking medication for conditions like diabetes or high cholesterol, or if you've ever had cancer.
Could this study suit you?
Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.
- Are you between 18 and 70 years old?
- Do you have normal kidney function?
- Is your blood pressure normal without medication?
- Have you never had cancer?
- Do you not have any metal implants unsafe for MRI (like a pacemaker)?
- Are you not pregnant and don't have severe claustrophobia?
What does participation involve?
This study involves attending a research centre for MRI scans. You will undergo no medication or invasive procedures. The exact number of visits and the full duration of your participation will be explained in detail by the study team, but generally it involves receiving MRI scans. You will not need to follow any specific diet, medication schedule or follow-up plan after scans. The total duration of your involvement will be clearly outlined in the consent process.
Potential risks and benefits
Locations (4)
- Aarhus University HospitalVerified postcodeAarhus, Denmark· Not yet recruiting
- University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg UniversityVerified postcodeMannheim, Germany· Not yet recruiting
- IRCCS Azienda Ospedaliero-Universitaria di BolognaVerified postcodeBologna, Italy· Recruiting
- Clínica Universidad de NavarraVerified postcodePamplona, Spain· Not yet recruiting
Common questions
What is multiparametric renal MRI?
It's a special, detailed type of MRI scan that gives doctors lots of information about your kidneys, beyond a standard picture.
Why is this study important?
It helps make sure these advanced kidney scans give reliable and consistent results, so they can be used more widely to help patients.
What is a 1.5T scanner?
It refers to the strength of the MRI machine. 1.5T scanners are common in many hospitals and clinics.
Will I get any results from my scan?
This study is for research, so you won't get specific results about your individual kidney health. The focus is on how well the scanning method itself works.
How long will my involvement last?
The study team will tell you the exact number of visits and the total time commitment when you discuss joining.
How to find out more
Matias Trillini, M.D.
Always speak to your GP or specialist before deciding to take part in a study.
Interested in taking part?
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