RecruitingOBSERVATIONAL

WAMIF: Prospective Study in Young Women Presenting Acute Myocardial Infarction: Cohort Follow up

This study is called WAMIF and it focuses on women under 50 who have had a heart attack. Researchers initially followed these women for up to 12 months after their heart attack to learn about their health and recovery. They gathered information about their health, lifestyle, and how well they were doing. The study found that many had risk factors like smoking. Now, the WAMIF team wants to check in with these women again, years later, to see how they are doing in the long term. This extended check-up will provide really important information to help doctors better understand heart attacks in young women and improve their care going forward. They also want to understand their quality of life and mental health after the event.

At a glance

Status

Recruiting

Sponsor

French Cardiology Society

Enrolment target

314

Start

25 Nov 2025

Estimated completion

30 Sep 2029

Myocardial Infarction, Acute

What is this study about?

This study, called WAMIF, is about understanding heart attacks in women under the age of 50. Heart attacks are unfortunately becoming more common in younger women, and doctors want to learn as much as possible to provide the best care.

The first part of the WAMIF study looked at 314 women in France who had a heart attack between 2017 and 2019. The researchers carefully collected information about their health, their lifestyle, and how they recovered in the first year. They found that many of these women had common risk factors like smoking. They also saw that most women experienced chest pain and that a small number had heart attacks caused by things other than blocked arteries, like tears in the heart's blood vessels or issues without clear blockages.

The good news is that after one year, most women in the original study were doing very well, with very few serious problems. This was a positive finding compared to previous studies. Now, the new phase of this study wants to check in with these women again, years later. This helps doctors understand what happens in the long run. By continuing to follow these women, the researchers hope to gather vital information that will help improve how heart attacks are prevented and treated in young women in the future. They also want to understand how a heart attack has affected their daily life and emotional well-being over time.

Key takeaways

This study is about understanding heart attacks in women under 50.
It's an extension of a previous study that followed women for a year after their heart attack.
The new study aims to check on their health and emotional well-being years later.
Participation involves filling out questionnaires, not new medications or complicated tests.
Your involvement helps improve future care for other young women.
You can stop participating at any time.

Who may be eligible?

To take part in this extended study, you must have been one of the original women who participated in the first WAMIF study.

This means you had a heart attack before the age of 50 and were part of the initial research between 2017 and 2019 in France.

The study is specifically looking for women who are willing and able to continue being part of this important long-term follow-up.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

Were you part of the original WAMIF study?
Did you have a heart attack before your 50th birthday?
Did your heart attack occur between 2017 and 2019?
Are you willing to complete questionnaires about your current health and well-being?

Answer every question to see your result.

What does participation involve?

If you decide to take part in this extended follow-up, you won't need to take any new medications. The main thing you'll be asked to do is complete some questionnaires. These questionnaires will ask about your current health, your quality of life, and your mental well-being to see how you're doing now, years after your heart attack. There will likely be a follow-up appointment or a way to submit this information. The duration of this follow-up will depend on the study's plan, but it's focused on gathering information about your health over a longer period.

Potential risks and benefits

By taking part, you’ll be contributing to valuable research that could help improve care for other young women who have heart attacks in the future. There are no known physical risks associated with simply answering questionnaires. The main benefit is knowing you're helping doctors understand this condition better. You are free to withdraw from the study at any time without giving a reason, and it will not affect your medical care.

Locations (1)

Hôpital de la Pitié Salpétrière
Verified postcode
Paris, France· Recruiting

Common questions

What is a 'myocardial infarction'?

It's the medical term for a heart attack, which happens when blood flow to part of the heart is blocked.

Why is this study only for women?

Heart attacks can affect women differently than men, especially younger women, so this study focuses specifically on understanding their unique experiences and outcomes.

What does 'follow-up' mean in this study?

It means the researchers want to check in with the original participants over time to see how their health and recovery have progressed long-term.

Will I have to do any complex tests?

No, this extended follow-up primarily involves answering questionnaires about your health, quality of life, and emotional well-being.

What will researchers do with my information?

Your information will be combined with that of other participants to help doctors learn more about heart attacks in young women and improve future care.

How to find out more

Tessa BERGOT, MSc

tessa.bergot@sfcardio.fr +33144907033 Official trial record

Always speak to your GP or specialist before deciding to take part in a study.