RecruitingOBSERVATIONAL

Research Biobank From Neuromuscular Biopsy Residues (in the Context of Care)

This project, called "COLMYONEU," is gathering extra muscle and nerve tissue that's left over from biopsies people have as part of their regular care at Bordeaux University Hospital. These biopsies are for diagnosing muscle, nerve, or related conditions. Researchers want to create a special collection, or 'biobank', of these samples. By studying these samples, they hope to get a much clearer picture of what causes these diseases and how they develop. This better understanding could lead to new ways to diagnose and treat these conditions in the future. Importantly, taking part doesn't involve any extra tests or procedures for you; it simply uses tissue that would otherwise be discarded.

At a glance

Status

Recruiting

Sponsor

University Hospital, Bordeaux

Enrolment target

500

Start

26 Jun 2023

Estimated completion

25 Jun 2053

Neuromuscular Diseases Muscle Nerve

What is this study about?

Imagine your body as a complex machine. Sometimes, parts of that machine, like your muscles or nerves, don't work quite right. Doctors often take a small piece of tissue, called a biopsy, to look closely at these parts and understand why. This study, called COLMYONEU, is collecting the tiny bits of muscle and nerve tissue that are left over after your doctors have taken what they need for your diagnosis.

Think of it like this: after a baker makes bread, there might be a little bit of dough left. Instead of throwing it away, this project is carefully collecting and storing these leftover bits of tissue. They do this because studying these human samples can give researchers vital clues about how muscle and nerve diseases work. Even with amazing advancements in science, there's still so much to learn, especially directly from human tissue.

The main goal is to build a high-quality 'biobank' – a carefully stored collection of these samples. By having a large collection, scientists can study many different cases and try to find common patterns or new insights. This information is incredibly valuable and could help speed up the discovery of new treatments or better ways to manage these conditions in the future.

Key takeaways

Uses leftover tissue from routine muscle/nerve biopsies.
Aims to create a collection (biobank) for research.
No extra tests, appointments, or procedures for you.
Helps scientists understand muscle and nerve diseases better.
Your identity will be kept confidential.
You can change your mind at any time.

Who may be eligible?

This study is looking for patients who have had a muscle or nerve biopsy at Bordeaux University Hospital. This includes adults and children who are being treated for conditions that affect their muscles or nerves, or related diseases.

Specifically, if you've been seen by the neurology, neuropediatrics (child nerve disorders), rheumatology (joint and muscle inflammation), or medical genetics departments for a suspected muscle or nerve condition, you might be included.

There are no reasons that would automatically exclude you from taking part, as long as your biopsy was done at the Bordeaux University Hospital and fits the criteria mentioned.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

Have I had a muscle, nerve, or related biopsy?
Was my biopsy performed at Bordeaux University Hospital?
Am I being treated for a suspected muscle, nerve, or related condition?
Am I willing for leftover biopsy tissue to be used for research?

Answer every question to see your result.

What does participation involve?

Taking part in this study is very straightforward and requires no extra effort or changes to your care. You won't need to make any additional visits to the hospital, have any extra tests, or take any new medications. The study simply uses a small amount of tissue that is left over from a muscle or nerve biopsy you've already had as part of your normal medical care.

Your involvement starts and ends with just allowing researchers to store and use these leftover samples. There's no ongoing follow-up for the study itself, and it doesn't involve any active participation from you after you've given your permission to use the samples. It's about using what's already collected to help future research.

Potential risks and benefits

There are no direct benefits or risks to you personally if you participate in this study. You will not receive any treatment or tests as part of this research. The potential benefit is that your stored tissue samples could contribute significantly to scientific knowledge, helping researchers better understand muscle and nerve diseases, which might lead to new treatments for others in the future. You have the right to change your mind and withdraw your consent for your samples to be used at any time, without affecting your medical care.

Locations (1)

Université Hospital, Bordeaux
Verified postcode
Bordeaux, France· Recruiting

Common questions

What is a 'biobank'?

A biobank is like a special library for biological samples (like tissue or blood), carefully stored for future research. This allows scientists to study many samples over time.

Will I need to have another biopsy for this study?

No, absolutely not. This study only uses leftover tissue from a biopsy you've already had as part of your regular medical diagnosis or treatment.

Will taking part affect my medical care at Bordeaux University Hospital?

No, your medical care will not be affected in any way. Your decision to participate or not participate is completely separate from your treatment.

Who will have access to my tissue samples and information?

Only approved researchers working on muscle and nerve diseases will be able to access the samples. Your personal details will be kept private and anonymised, meaning your identity won't be linked directly to the tissue.

Can I change my mind after agreeing to participate?

Yes, you have the right to withdraw your consent at any time without giving a reason. Just let your doctor or the study team know, and your samples will no longer be used for research.

How to find out more

Marie Laure NEGRIER, Pr

marie-laure.martin-negrier@chu-bordeaux.fr 0557821818 Official trial record

Always speak to your GP or specialist before deciding to take part in a study.