Not yet recruitingNAINTERVENTIONAL

The Efficacy of Combining Music Intervention With Nicotine Replacement Therapy to Reduce Smoking Craving, Among Healthcare Professionals Who Are Trying to Quit.

This research is trying to find better ways to help healthcare workers stop smoking. It's a small study that will test if adding music therapy to nicotine patches works better than patches alone to reduce cravings. Smoking causes serious health problems, and while many healthcare professionals help others quit, some smoke themselves. Understanding why some people successfully quit smoking and others don't is key. This study will also look into changes in gut bacteria and how genes work, comparing smokers who quit, active smokers, and people who have never smoked. This extra part of the study aims to understand the body's response to quitting, which could lead to new ways to support people stopping smoking.

At a glance

Status

Not yet recruiting

Phase

Sponsor

Poitiers University Hospital

Enrolment target

Start

01 Mar 2026

Estimated completion

01 Feb 2030

Nicotine Replacement Therapy Healthcare Professionals Tobacco Craving Tabacco Cessation

What is this study about?

This study is particularly interested in helping healthcare professionals who smoke to quit. We know that smoking is a major cause of illness and death, and even though healthcare workers often advise others to stop, some of them also smoke. This can make it harder for them to help their patients effectively.

The main part of this study will look at how well a combination of music therapy and nicotine patches works compared to just using nicotine patches, for reducing cravings in people trying to stop smoking. We hope to recruit about 50 healthcare professionals for this. By doing this, we want to see if adding music can make it easier for people to manage their desire to smoke and ultimately quit.

Quitting smoking can be very difficult, and many people unfortunately start smoking again within the first year. This study also aims to understand what factors make someone more likely to successfully quit and stay smoke-free. An extra part of the study, called MUSICAT-BIO, will investigate changes in the body, specifically looking at gut bacteria and certain gene activities, in people who quit smoking, people who are still smoking, and people who have never smoked. This comparison could give us important clues about how quitting smoking affects our bodies and why some people find it easier to quit than others.

Key takeaways

This study aims to help healthcare professionals quit smoking.
It combines nicotine patches with music therapy for reducing cravings.
The study also investigates why some people successfully quit smoking and how quitting affects gut health.
Participants must be motivated to quit smoking and smoke at least 6 cigarettes daily.
There are specific health and medication criteria for joining, including for a non-smoking comparison group.

Who may be eligible?

To join this study, you need to be a healthcare professional aged 18 or over. You must be currently smoking at least six cigarettes a day and have been doing so for at least six months. Most importantly, you need to be genuinely motivated to quit smoking. You'll also need to sign a consent form, showing you understand what the study involves.

There are some reasons why you might not be able to take part. For example, if you have severe depression that isn't stable, certain mental health conditions, or other serious addictions like alcoholism. Also, if you've recently used other medications or methods to quit smoking in the last three months, or if you have a condition that means you can't use nicotine replacement therapy, you wouldn't be able to join. We also can't include people who are already taking part in another clinical study.

For the extra part of the study (MUSICAT-BIO), if you want to be in the group of people who don't smoke, you must never have smoked before, used e-cigarettes (even nicotine-free ones), or have certain long-term illnesses or be taking specific medications like steroids or antibiotics in the last three weeks.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

Are you a healthcare professional?
Are you 18 years old or older?
Do you smoke at least 6 cigarettes per day?
Are you genuinely motivated to quit smoking?
Have you not used other stop-smoking aids in the last 3 months?
Do you have no medical conditions that prevent you from using nicotine patches?

Answer every question to see your result.

What does participation involve?

The specific details of what taking part involves, such as the number of visits, types of assessments, and overall duration of the study, are not fully described in the summary provided. However, generally, if you join a study like this, you would likely: receive either nicotine replacement therapy alone or with music intervention; have regular check-ups to monitor your progress and health; and provide biological samples (like for gut bacteria analysis) if you are part of the MUSICAT-BIO group. The music intervention would involve listening to music. You might also fill out questionnaires about your cravings and smoking habits. The study will continue until visit V4, but the total number of visits and follow-up period are not specified.

Potential risks and benefits

Taking part in this study could offer you the benefit of extra support in your journey to quit smoking, potentially making the process easier and increasing your chances of success. It might also help us understand more about how our bodies react to quitting. However, there are potential risks, such as side effects from nicotine replacement therapy, or the time commitment required for study visits and interventions. As with any study, you have the right to withdraw at any time for any reason, and this will not affect your usual medical care.

Locations (1)

Poitiers University Hospital
Verified postcode
Poitiers, France

Common questions

What kind of music therapy is involved?

The study does not specify the exact type of music, but it's used alongside nicotine patches to help reduce smoking cravings.

Will I know if I'm getting music therapy or just patches?

Because it's a 'randomised controlled trial', you might not know which group you're in until after the study, which helps make the results fair.

What are biological collections?

These are samples like stool or blood, taken to study things like your gut bacteria or genetic changes related to quitting smoking.

What happens if I stop smoking before the study ends?

The study is designed to help you quit, so successful quitting would be a positive outcome. Your progress would still be monitored as part of the study.

Is my information kept private?

Yes, all clinical trials are required to protect your personal information and keep your involvement confidential.

How to find out more

Claire LAFAY-CHEBASSIER, MD

claire.lafay-chebassier@chu-poitiers.fr 05 49 44 38 36 Official trial record

Always speak to your GP or specialist before deciding to take part in a study.