Neoadjuvant and Adjuvant Treatment in Resectable Non-small Cell Lung Cancer

To join this study, you would generally need to have been recently diagnosed with a specific type of non-small cell lung cancer (stages IIA to IIIB) that your doctors believe can be fully removed by surgery. You would also need to be in generally good health, able to perform daily activities without too much difficulty, and have healthy organs and bone marrow.

There are also some reasons why you might not be able to join. For example, if your cancer has certain genetic changes (like specific EGFR mutations or ALK translocations), or if you have a history of serious autoimmune conditions, severe heart problems, or other serious uncontrolled illnesses. Also, if you already have certain lung conditions, like active interstitial lung disease, or if your doctors plan to remove only a small piece of your lung rather than the whole lobe or larger section, you might not be able to take part. Your medical team will carefully check all your health details to see if this study is right for you.

If you join this study, you will be assigned to one of several treatment groups at random, like flipping a coin. You won't get to choose your specific treatment combination. You will receive medication through injections, infusions (drips), or tablets for a period before your surgery, and then likely continue with some of these medications after your surgery for a longer time, possibly up to a year or more. You'll have regular hospital visits for medical checks, blood tests, scans (like CT scans), and to talk to the study doctors and nurses. These visits will check how you're responding to the treatment and look for any side effects. The total time you're involved in the study, including follow-up appointments after your treatment ends, could be several years.