PROspective Master-protocol for Evaluation of Systemic THErapeutics in Elderly With Thoracic Malignancies

To be considered for this study, you need to be at least 70 years old and have a specific type of lung cancer called non-small cell lung cancer, for which your medical team has recommended treatment that affects your whole body. Crucially, you must not have received any previous treatment of this kind for your lung cancer.

You also need to be covered by social security and eligible for the recommended treatments. The treatments being used must be approved and generally available, or accessible through specific early or compassionate access programmes. You should be able to understand what the study involves and agree for your health information to be collected. Finally, you would need to sign a consent form to officially join the study.

However, you won't be able to join if you are under the care of a legal guardian or curator, or if you're not a regular patient at the clinic conducting the study. Also, if you've already had a 'systemic' treatment (treatment that works throughout the body) for your non-small cell lung cancer, you won't be eligible.

If you decide to take part in this study, you would continue to receive your usual medical care from your doctors. This means you would attend regular clinic visits as requested by your doctor. During these visits, they would check your general health, how well your treatment is working, and if you're experiencing any side effects.

You would also have standard medical tests, such as blood tests, scans (like X-rays or CT scans), and possibly another biopsy if needed. In addition, you would be asked to provide blood samples for a special collection called a bio-bank. These samples could be used for future research. You'd also complete some special assessments for older adults and fill in three questionnaires about your quality of life.